Current address: University of South Alabama, Mobile, Alabama.
Efficacy, tolerability, and safety of rapid initiation of topiramate versus phenytoin in patients with new-onset epilepsy: A randomized double-blind clinical trial
Article first published online: 14 JUL 2010
Wiley Periodicals, Inc. © 2010 International League Against Epilepsy
Volume 51, Issue 10, pages 1970–1977, October 2010
How to Cite
Ramsay, E., Faught, E., Krumholz, A., Naritoku, D., Privitera, M., Schwarzman, L., Mao, L., Wiegand, F., Hulihan, J. and for the CAPSS-272 Study Group (2010), Efficacy, tolerability, and safety of rapid initiation of topiramate versus phenytoin in patients with new-onset epilepsy: A randomized double-blind clinical trial. Epilepsia, 51: 1970–1977. doi: 10.1111/j.1528-1167.2010.02670.x
Clinical trial registration: ClinicalTrials.gov identifier: NCT00210782. (Study identifier: CR004663) A Comparison of the Effectiveness and Safety of Topiramate and Phenytoin in Subjects with New Onset Epilepsy Requiring Rapid Initiation of Antiepileptic Drug Treatment.
- Issue published online: 14 JUL 2010
- Article first published online: 14 JUL 2010
- Accepted May 17, 2010; Early View publication July 14, 2010.
Figure S1. Study flow diagram.
Table S1. Study AED exposure and blood levels during the double-blind phase (safety analysis set).
Table S2. Inferential tests for treatment difference in time to first GTC or complex partial seizure during the double blind phase (ITT analysis set).
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