DRAVET SYNDROME

The ketogenic diet for Dravet syndrome and other epileptic encephalopathies: An Italian consensus

  1. Pierangelo Veggiotti1,
  2. Alberto Burlina2,
  3. Giangennaro Coppola3,
  4. Raffaella Cusmai4,
  5. Valentina De Giorgis1,
  6. Renzo Guerrini5,
  7. Anna Tagliabue6,
  8. Bernardo Dalla Bernardina7

Article first published online: 4 APR 2011

DOI: 10.1111/j.1528-1167.2011.03010.x

Issue

Epilepsia

Epilepsia

Special Issue: Severe Myoclonic Epilepsy – Dravet Syndrome: Thirty Years Later

Volume 52, Issue Supplement s2, pages 83–89, April 2011

Additional Information

How to Cite

Veggiotti, P., Burlina, A., Coppola, G., Cusmai, R., De Giorgis, V., Guerrini, R., Tagliabue, A. and Bernardina, B. D. (2011), The ketogenic diet for Dravet syndrome and other epileptic encephalopathies: An Italian consensus. Epilepsia, 52: 83–89. doi: 10.1111/j.1528-1167.2011.03010.x

Author Information

  1. 1

    Department of Child Neurology and Psychiatry, Fondazione IRCCS Istituto Neurologico C. Mondino, Pavia, Italy

  2. 2

    Division of Inborn Metabolic Diseases, Department of Pediatrics, University Hospital Padova, Padova, Italy

  3. 3

    Department of Child Neuropsychiatry, University of Naples, Naples, Italy

  4. 4

    Division of Neurology, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

  5. 5

    Pediatric Neurology Unit and Laboratories, Children's Hospital A. Meyer, University of Florence, Florence, Italy

  6. 6

    Nutrition and Eating Disorder Research Center, University of Pavia, Pavia, Italy

  7. 7

    Unit of Child Neuropsychiatry, University of Verona, Verona, Italy

*Address correspondence to Pierangelo Veggiotti, Department of Child Neurology and Psychiatry, Fondazione IRCCS Istituto Neurologico C. Mondino, Pavia, Italy. E-mail: pveggiot@unipv.it

Publication History

  1. Issue published online: 4 APR 2011
  2. Article first published online: 4 APR 2011

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Keywords:

  • Ketogenic diet;
  • Clinical management;
  • Drug-resistant epilepsy

Summary

Ketogenic diet is a nonpharmacologic treatment for childhood epilepsy not amenable to drugs. At the present time, two works based on national research, one in Germany and one in the United States provide international guidelines to ensure a correct management of the ketogenic diet. Our Italian collaborative study group was set up in order to formulate a consensus statement regarding the clinical management of the ketogenic diet, patient selection, pre–ketogenic diet, counseling, setting and enforcement of dietary induction of ketosis, follow-up management, and eventual discontinuation of the diet.

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