FULL-LENGTH ORIGINAL RESEARCH

Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood–brain barrier leakage but not microglia activation

  1. Erwin A. van Vliet1,2,
  2. Grazia Forte1,
  3. Linda Holtman1,
  4. Jeroen C. G. den Burger3,
  5. Arno Sinjewel3,
  6. Helga E. de Vries4,
  7. Eleonora Aronica5,
  8. Jan A. Gorter1,2

Article first published online: 21 MAY 2012

DOI: 10.1111/j.1528-1167.2012.03513.x

Issue

Epilepsia

Epilepsia

Volume 53, Issue 7, pages 1254–1263, July 2012

Additional Information

How to Cite

van Vliet, E. A., Forte, G., Holtman, L., den Burger, J. C. G., Sinjewel, A., de Vries, H. E., Aronica, E. and Gorter, J. A. (2012), Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood–brain barrier leakage but not microglia activation. Epilepsia, 53: 1254–1263. doi: 10.1111/j.1528-1167.2012.03513.x

Author Information

  1. 1

    Swammerdam Institute for Life Sciences, Center for Neuroscience, University of Amsterdam, Amsterdam, The Netherlands

  2. 2

    Epilepsy Institute in The Netherlands Foundation (Stichting Epilepsie Instellingen Nederland, SEIN), Heemstede, The Netherlands

  3. 3

    Department of Clinical Pharmacology and Pharmacy, VU University Medical Center, Amsterdam, The Netherlands

  4. 4

    Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands

  5. 5

    Academic Medical Center, Department of (Neuro) Pathology, University of Amsterdam, Amsterdam, The Netherlands

*Address correspondence to Dr. Jan. A. Gorter, Swammerdam Institute for Life Sciences, Center for Neuroscience, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands. E-mail: j.a.gorter@uva.nl

Publication History

  1. Issue published online: 3 JUL 2012
  2. Article first published online: 21 MAY 2012
  3. Accepted March 23, 2012; Early View publication May 21, 2012.

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