Skin manifestations of hormone-secreting tumors
Article first published online: 3 NOV 2010
© 2010 Wiley Periodicals, Inc.
Volume 23, Issue 6, pages 643–650, November/December 2010
How to Cite
Jabbour, S. A. (2010), Skin manifestations of hormone-secreting tumors. Dermatologic Therapy, 23: 643–650. doi: 10.1111/j.1529-8019.2010.01369.x
- Issue published online: 3 NOV 2010
- Article first published online: 3 NOV 2010
Endocrine and metabolic diseases, besides affecting other organs, can result in changes in cutaneous function and morphology and can lead to a complex symptomatology. Dermatologists may see some of these skin lesions first, either before the endocrinologist, or even after the internist or specialist has missed the right diagnosis. Because some skin lesions might reflect a life-threatening endocrine or metabolic disorder, identifying the underlying disorder is very important, so that patients can receive corrective rather than symptomatic treatment.
In this issue, we will review various hormone-secreting tumors, including pituitary disorders (Cushing's syndrome and acromegaly), hyperthyroidism, glucagonoma, carcinoid syndrome, mastocytosis, and hyperandrogenism. We will focus on clinical manifestations, mainly cutaneous, followed by a brief discussion on how to make the diagnosis of each condition in addition to treatment options.