Conflict of interest: None.
Diagnosis and treatment of cutaneous paraneoplastic disorders
Version of Record online: 3 NOV 2010
© 2010 Wiley Periodicals, Inc.
Volume 23, Issue 6, pages 662–675, November/December 2010
How to Cite
Abreu Velez, A. M. and Howard, M. S. (2010), Diagnosis and treatment of cutaneous paraneoplastic disorders. Dermatologic Therapy, 23: 662–675. doi: 10.1111/j.1529-8019.2010.01371.x
- Issue online: 3 NOV 2010
- Version of Record online: 3 NOV 2010
- paraneoplastic disorders;
- skin manifestations
The skin plays a critical role in the detection of internal malignances. Cutaneous signs of these disorders afford clinicians opportunities for early diagnosis and treatment. We aim to succinctly review the recognition, diagnosis, and treatment of selected cutaneous paraneoplastic diseases. Skin disorders that may be associated with paraneoplastic syndromes include: cutaneous metastases, tripe palms, Sweet's syndrome, glucagonoma, Paget's disease and extramammary Paget's disease, acanthosis nigricans, Birt-Hogg-Dube syndrome, basal cell nevus syndrome, Bazex syndrome (acrokeratosis paraneoplastica), carcinoid syndrome, Cowden's disease(multiple hamartoma syndrome), dermatomyositis, erythema gyratum repens, ichthyosis aquisita, von Recklinghausen's disease, pityriasis rotunda, pyoderma gangrenosum, Quincke's edema (angioedema and paraneoplastic uricaria), paraneoplastic pemphigus, Degos' disease, superior vena cava syndrome, Werner's syndrome, diffuse normolipemic plane xanthomas, and yellow nail syndrome. Treatment for these disorders depends on the nature and anatomic distribution of the primary neoplastic process.