THERAPEUTIC HOTLINE: Successful treatment of Morbihan's disease with oral prednisolone and doxycycline


Harneet Ranu, MBBS, MRCP (UK), MMED Int Med (Sing), MSc Clin Derm (Lond), Registrar in Dermatology, National Skin Center, 1 Mandalay Road, 308205, Singapore, or email:


Persistent facial swelling can occur as a rare complication of rosacea. This finding is referred to as lymphedematous rosacea or Morbihan's disease. We report a case of a 45-year-old male with no previous history of rosacea who developed bilateral periorbital swelling associated with facial erythema and edema that responded to a combination of oral corticosteroids and doxycycline. Biopsy revealed changes of granulomatous rosacea.