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Chondrodermatitis nodularis chronica helicis and photodynamic therapy: a new therapeutic option?
Article first published online: 30 JAN 2011
© 2011 Wiley Periodicals, Inc.
Volume 24, Issue 1, pages 144–147, January/February 2011
How to Cite
Pellegrino, M., Taddeucci, P., Mei, S., Peccianti, C. and Fimiani, M. (2011), Chondrodermatitis nodularis chronica helicis and photodynamic therapy: a new therapeutic option?. Dermatologic Therapy, 24: 144–147. doi: 10.1111/j.1529-8019.2010.01389.x
Each author agrees to allow the corresponding author to serve as primary correspondent with the editorial office. We have no relevant financial interest in this manuscript.
- Issue published online: 30 JAN 2011
- Article first published online: 30 JAN 2011
- chondrodermatitis nodularis chronica helicis;
- photodynamic therapy
Chondrodermatitis nodularis chronica helicis (CNCH) is a fairly frequent disorder of unknown etiology. Although the elective therapy is surgery, local application of topical steroids, antibiotic ointments, intralesional injection of collagen, cryotherapy, curettage followed by diathermy, and CO2 laser treatment have also been proposed. The aim of the study was to test the utility of photodynamic therapy (PDT) for CNCH. Two patients with painful CNCH underwent PDT with a 635 nm light source for 20 minutes (70 J/cm2) after application of cream containing 20% 5-aminolevulinic acid (5-ALA) and occlusion for 3 hours. The lesions decreased considerably in size and pain ceased within a few weeks. The results suggest that this method can be useful for treating CNCH, especially in patients with contraindications for surgery.