Approach to the patient with autoimmune mucocutaneous blistering diseases
Version of Record online: 15 MAR 2011
© 2011 Wiley Periodicals, Inc.
Volume 24, Issue 2, pages 173–186, March/April 2011
How to Cite
Sami, N. (2011), Approach to the patient with autoimmune mucocutaneous blistering diseases. Dermatologic Therapy, 24: 173–186. doi: 10.1111/j.1529-8019.2011.01393.x
- Issue online: 15 MAR 2011
- Version of Record online: 15 MAR 2011
- autoimmune blistering diseases;
- bullous lupus;
- dermatitis herpetiformis;
- herpes gestationis;
- linear IgA bullous disease;
- paraneoplastic pemphigus;
- subcorneal pustular dermatosis
Autoimmune mucocutaneous blistering diseases (AMBD) are a rare group of dermatoses that can be potentially fatal. There are many subtypes and their clinical presentation can vary from being localized to general involvement. It is crucial that a diagnosis be made as early as possible and appropriate treatments are implemented. This article will discuss the diagnosis and available treatments of the major AMBDs. There are very few case-controlled studies regarding the treatments of these diseases. Most of the treatments used for these diseases are based on anecdotal reports. Hence, a synopsis of the conventional treatments and some brief recommendations will also be discussed. A brief discussion regarding “rescue” therapies that have been used for those patients with more recalcitrant cases of AMBD will also be presented.