Fractional CO2 laser: a novel therapeutic device for refractory necrobiosis lipoidica
Article first published online: 4 DEC 2012
© 2012 Wiley Periodicals, Inc.
Volume 25, Issue 6, pages 612–614, November/December 2012
How to Cite
Buggiani, G., Tsampau, D., Krysenka, A., De Giorgi, V. and Hercogová, J. (2012), Fractional CO2 laser: a novel therapeutic device for refractory necrobiosis lipoidica. Dermatologic Therapy, 25: 612–614. doi: 10.1111/j.1529-8019.2012.01531.x
- Issue published online: 4 DEC 2012
- Article first published online: 4 DEC 2012
- CO2 laser;
- necrobiosis lipoidica;
Necrobiosis lipoidica diabeticorum is a granulomatous skin disease of uncertain pathogenesis. Many therapeutic approaches have been reported in the literature, but none of them can be considered the gold standard. Fractional CO2 laser treatment shows peculiar effects in the skin, mainly due to its ability of modulating cytokine pathways of tissue-repairing mechanisms. Thus, we propose fractional CO2 laser in the management of refractory necrobiosis lipoidica in selected recalcitrant patients.