Pruritic papular eruption in HIV: a case successfully treated with NB-UVB

Authors

  • Sara Bellavista,

    Corresponding author
    • Section of Dermatology and Venereology, Department of Internal Medicine, Geriatrics and Nephrology, University of Bologna, Bologna, Italy
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  • Antonietta D' Antuono,

    1. Section of Dermatology and Venereology, Department of Internal Medicine, Geriatrics and Nephrology, University of Bologna, Bologna, Italy
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  • Salvatore Domenico Infusino,

    1. Section of Dermatology and Venereology, Department of Internal Medicine, Geriatrics and Nephrology, University of Bologna, Bologna, Italy
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  • Roberto Trimarco,

    1. Section of Dermatology and Venereology, Department of Internal Medicine, Geriatrics and Nephrology, University of Bologna, Bologna, Italy
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  • Annalisa Patrizi

    1. Section of Dermatology and Venereology, Department of Internal Medicine, Geriatrics and Nephrology, University of Bologna, Bologna, Italy
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Address correspondence and reprint requests to: Sara Bellavista, MD, Section of Dermatology and Venereology, Department of Internal Medicine, Geriatrics and Nephrology, Division of Dermatology, Sant'Orsola- Malpighi Hospital, Via Massarenti 1, 40138 Bologna, or email: sara.bellavista4@unibo.it.

Abstact

Pruritic papular eruption (PPE) is a skin disease characterized by the eruption of itching papules on the extremities, face, and trunk; it is quite frequent in HIV-positive patients especially during the advanced immunosuppressive stage. PPE usually improves or heals when antiretroviral therapy restores the immune system function, but in some cases, it can take several months, and a symptomatic treatment for PPE is required. Systemic antihistamines, topical steroids, topical tacrolimus, itraconazole, pentoxyphilline, and ultraviolet B phototherapy have been proposed in cases of persisting PPE, but an elective treatment has not yet been found. We describe the case of a black patient affected by PPE, nonimproving with antiretroviral treatment, and resistant to topical steroids and oral antihistamines; a satisfactory and speedy result was achieved with narrow-band ultraviolet B phototherapy.

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