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Blood and breath acetaldehyde levels were measured following ethanol ingestion (0.5 ml/kg) In 11 boys familially at risk for alcoholism and 11 age-matched controls. No significant differences were found between groups for acetaldehyde, objective, or subjective measures of intoxicatlon. Previous reports of acetaldehyde as a marker of risk for aloholism were not confined.

Baseline behavioral state predicted response to alcohol. Children tended to have a subjective response in a direction opposite from the baseline mood state.