Fetal Alcohol Syndrome: A Case Report of Neuropsychological, MRI, and EEG Assessment of Two Children


  • This research was supported in part by National Institute on Alcohol Abuse and Alcoholism grant numbers AA06902 and AA03249 to EPR, National Institute of Neurological Disorders and Stroke, grant number NS22343 for the Center for the Study of the Neurological Basis of Language, National Institute of Child Health and Human Development grant number HD26022 to UB. and General Clinical Research Center grant number RR00833 to Scripps Clinic.

Reprint requests: Dr. E. P. Riley, Department of Psychology, San Diego State University, San Diego, CA 92182-0350.


Neuropsychological, neuroanatomical, and electrophysiological data are presented on two subjects with fetal alcohol syndrome (FAS). Both boys had intelligence quotients in the mentally deficient range and were found to have several other severe, specific deficits. Magnetic resonance imaging showed abnormalities of the corpus callosum, and reductions in the size of the basal ganglia and thalamic structures. No focal abnormalities were noted in the electroencephalogram records, although the electroencephalograms of both boys were moderately abnormal for their age group. A multidisciplinary approach to the study of FAS, hopefully will lead to a more unified concept of the disorder and perhaps indicate specific areas of vulnerability.