This work was supported by Grants ROI-AA06966 and P50-AAO706 from the National Institute of Alcohol Abuse and Alcoholism, with supplemental support from Minority Biomedical Research Support Grant S06-RR08167 from the National Institutes of Health.
Effects of Prenatal Exposure to Alcohol, Smoking, and Illicit Drugs on Postpartum Somatic Growth
Article first published online: 11 APR 2006
Alcoholism: Clinical and Experimental Research
Volume 18, Issue 2, pages 317–323, April 1994
How to Cite
Jacobson, J. L., Jacobson, S. W. and Sokol, R. J. (1994), Effects of Prenatal Exposure to Alcohol, Smoking, and Illicit Drugs on Postpartum Somatic Growth. Alcoholism: Clinical and Experimental Research, 18: 317–323. doi: 10.1111/j.1530-0277.1994.tb00020.x
- Issue published online: 11 APR 2006
- Article first published online: 11 APR 2006
- Received for publication April 16, 1993; accepted September 20. 1993
- Physical Growth;
- Prenatal Alcohol Exposure;
- Fetal Alcohol Effects;
- Maternal Smoking;
The association of fetal growth retardation with prenatal exposure to alcohol, smoking, opiates, and cocaine is well documented, but relatively little is known about the effects of these exposures on postpartum growth. This study assessed physical growth from birth through 6.5 and 13 months in 412 black, inner-city infants recruited on the basis of their mothers' use of alcohol and/or cocaine during pregnancy. Prenatal alcohol exposure was associated with a slower rate of growth during the first 6.5 postpartum months. This postnatal growth retardation was associated with maternal drinking during a critical period–the latter part of gestation–and was not related to drinking at the time of conception or to postnatal exposure to alcohol from breast-feeding. By contrast, smoking and cocaine use during pregnancy were associated with faster postnatal weight gain. Although maternal smoking was correlated with shorter stature at 6.5 and 13 months, this effect was attributable to maternal drinking during pregnancy, suggesting that the association of maternal smoking with shorter childhood stature reported elsewhere may be due to prenatal alcohol exposure, which was not controlled in prior studies.