Supported by NIAAA Grants R37-AA02342 and P50-AA07611 (T-KL, VAR); R01-AA06434, R01-AA11835, and P50-AA07611 (DWC); R21-AA10831, P50-AA07611, and M01-RR750 (SO); and National Science Council Grant 89-2314-B016-028 and National Health Research Institutes Grant GT-EX89B939P (S-JY).
Genetic and Environmental Influences on Alcohol Metabolism in Humans
Article first published online: 11 APR 2006
Alcoholism: Clinical and Experimental Research
Volume 25, Issue 1, pages 136–144, January 2001
How to Cite
Li, T.-K., Yin, S.-J., Crabb, D. W., O'Connor, S. and Ramchandani, V. A. (2001), Genetic and Environmental Influences on Alcohol Metabolism in Humans. Alcoholism: Clinical and Experimental Research, 25: 136–144. doi: 10.1111/j.1530-0277.2001.tb02138.x
- Issue published online: 11 APR 2006
- Article first published online: 11 APR 2006
- Received for publication September 20, 2000; accepted November 11, 2000.
- ADH/ALDH Polymorphisms;
- Alcohol Clamping;
- Food Effects on Elimination
This manuscript represents the proceedings of a symposium at the 2000 RSA Meeting in Denver, Colorado. The organizer/chair was Ting-Kai Li. The presentations were: (1) Introduction to the Symposium, by Ting-Kai Li; (2) ALDH2 polymorphism and alcohol metabolism, by Shih-Jiun Yin; (3) ALDH2 promoter polymorphism and alcohol metabolism, by David W. Crabb; (4) Use of BrAC clamping to estimate alcohol elimination rates: Application to studies of the influence of genetic and environmental determinants, by Sean O'Connor; and (5) Effect of food and food composition on alcohol elimination rates as determined by clamping, by Vijay A. Ramchandani.