These authors contributed equally to this work.
Association of Moderate Alcohol Use and Binge Drinking During Pregnancy with Neonatal Health
Article first published online: 9 MAY 2011
Copyright © 2011 by the Research Society on Alcoholism
Alcoholism: Clinical and Experimental Research
Volume 35, Issue 9, pages 1669–1677, September 2011
How to Cite
Meyer-Leu, Y., Lemola, S., Daeppen, J.-B., Deriaz, O. and Gerber, S. (2011), Association of Moderate Alcohol Use and Binge Drinking During Pregnancy with Neonatal Health. Alcoholism: Clinical and Experimental Research, 35: 1669–1677. doi: 10.1111/j.1530-0277.2011.01513.x
- Issue published online: 25 AUG 2011
- Article first published online: 9 MAY 2011
- Received for publication December 31, 2009; accepted January 24, 2011.
- Prenatal Drinking;
- Binge Drinking;
- Neonatal Asphyxia
Background: Heavy drinking and smoking during pregnancy are known to have a negative impact on the unborn child. However, the impact of low-to-moderate alcohol consumption and binge drinking has been debated recently. The aim of this study was to examine the relationship of moderate prenatal drinking and binge drinking with birthweight, being small for gestational age (SGA) at birth, preterm birth, and neonatal asphyxia.
Methods: Moderate alcohol drinking, binge drinking, and several possible confounders were assessed in 1,258 pregnant women; information on neonatal health was obtained at birth.
Results: Results indicate that 30.8% of the women drank at low levels (<2 glasses/wk), 7.9% drank moderately (2 to 4 glasses/wk), and 0.9% showed higher levels of drinking (≥5 glasses/wk); 4.7% reported binge drinking (defined as ≥3 glasses/occasion). 6.4% of the children were SGA (<10th percentile of birthweight adjusted for gestational age), 4.6% were preterm (<37th week of gestation), and 13.0% showed asphyxia (arterial cord pH <7.10 and/or arterial cord lactate >6.35 mmol and/or Apgar score <7 at 5 minutes). When controlling for maternal age, citizenship, occupational status, parity, smoking, use of prescription/over-the-counter drugs, illicit drug use, and child gender moderate drinking was related to lower birthweight (p < 0.01), and moderate drinking and binge drinking were associated with neonatal asphyxia at trend level (p = 0.06 and p = 0.09). Moderate drinking and binge drinking were not related to length of gestation.
Conclusions: In contrast to recent reviews in the field, our results assume that moderate drinking and binge drinking are risk factors for neonatal health.