Limited Therapeutic Effect of N-Acetylcysteine on Hepatic Insulin Resistance in an Experimental Model of Alcohol-Induced Steatohepatitis
Article first published online: 25 JUL 2011
Copyright © 2011 by the Research Society on Alcoholism
Alcoholism: Clinical and Experimental Research
Volume 35, Issue 12, pages 2139–2151, December 2011
How to Cite
Setshedi, M., Longato, L., Petersen, D. R., Ronis, M., Chen, W. C., Wands, J. R. and de la Monte, S. M. (2011), Limited Therapeutic Effect of N-Acetylcysteine on Hepatic Insulin Resistance in an Experimental Model of Alcohol-Induced Steatohepatitis. Alcoholism: Clinical and Experimental Research, 35: 2139–2151. doi: 10.1111/j.1530-0277.2011.01569.x
- Issue published online: 18 NOV 2011
- Article first published online: 25 JUL 2011
- Received for publication August 4, 2010; accepted March 28, 2011.
Table S1. Primer pairs used for qRT-PCR assays.
Table S2. Effects of ethanol and NAC on markers of hepatocellular injury.
Table S3. Effects of ethanol and NAC on hepatic CYP2E1 activity and oxidative stress.
Table S4. Effects of ethanol and NAC on hepatic hydroxyproline content and expression of mRNAs associated with fibrosis and matrix remodeling.
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