A Role of Genomic Copy Number Variation in the Complex Behavioral Phenotype of Alcohol Dependence: A Commentary
Reprint requests: Alexander E. Urban, PhD, Department of Psychiatry and Behavioral Sciences, Department of Genetics, Stanford University School of Medicine, 1050A Arastradero Road, Room A233A, Palo Alto, CA 94304-5742; Tel.: 650-736-9528; Fax: 650-725-4913; E-mail: firstname.lastname@example.org
In their paper “Copy number variations in 6q14.1 and 5q13.2 are associated with alcohol dependence” Lin and colleagues report on the association between alcohol dependence and 2 duplication CNVs in the genome sequence, one containing 8 genes within its boundaries and another that contains no genes. In this commentary, I point out some of the opportunities and challenges that arise from such a finding.