Get access

Periodontal Disease and Weight Loss in Older Adults

Authors

  • Robert J. Weyant DMD, DrPH,

    1. From the *Department of Dental Public Health, Division of Geriatric Medicine, Department of Biostatistics, §Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PennsylvaniaDepartment of Preventive Medicine, Health Science Center, University of Tennessee, Memphis, TennesseePrevention Sciences Group, University of California at San Francisco, San Francisco, California#Laboratory of Epidemiology, Biometry and Demography, National Institute of Aging, National Institutes of Health, Bethesda, Maryland.
    Search for more papers by this author
  • Anne B. Newman MD, MPH,

    1. From the *Department of Dental Public Health, Division of Geriatric Medicine, Department of Biostatistics, §Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PennsylvaniaDepartment of Preventive Medicine, Health Science Center, University of Tennessee, Memphis, TennesseePrevention Sciences Group, University of California at San Francisco, San Francisco, California#Laboratory of Epidemiology, Biometry and Demography, National Institute of Aging, National Institutes of Health, Bethesda, Maryland.
    Search for more papers by this author
  • Stephen B. Kritchevsky PhD,

    1. From the *Department of Dental Public Health, Division of Geriatric Medicine, Department of Biostatistics, §Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PennsylvaniaDepartment of Preventive Medicine, Health Science Center, University of Tennessee, Memphis, TennesseePrevention Sciences Group, University of California at San Francisco, San Francisco, California#Laboratory of Epidemiology, Biometry and Demography, National Institute of Aging, National Institutes of Health, Bethesda, Maryland.
    Search for more papers by this author
  • Walter A. Bretz DDS, DrPH,

    1. From the *Department of Dental Public Health, Division of Geriatric Medicine, Department of Biostatistics, §Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PennsylvaniaDepartment of Preventive Medicine, Health Science Center, University of Tennessee, Memphis, TennesseePrevention Sciences Group, University of California at San Francisco, San Francisco, California#Laboratory of Epidemiology, Biometry and Demography, National Institute of Aging, National Institutes of Health, Bethesda, Maryland.
    Search for more papers by this author
  • Patricia M. Corby DMD,

    1. From the *Department of Dental Public Health, Division of Geriatric Medicine, Department of Biostatistics, §Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PennsylvaniaDepartment of Preventive Medicine, Health Science Center, University of Tennessee, Memphis, TennesseePrevention Sciences Group, University of California at San Francisco, San Francisco, California#Laboratory of Epidemiology, Biometry and Demography, National Institute of Aging, National Institutes of Health, Bethesda, Maryland.
    Search for more papers by this author
  • Dianxu Ren MS, MD,

    1. From the *Department of Dental Public Health, Division of Geriatric Medicine, Department of Biostatistics, §Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PennsylvaniaDepartment of Preventive Medicine, Health Science Center, University of Tennessee, Memphis, TennesseePrevention Sciences Group, University of California at San Francisco, San Francisco, California#Laboratory of Epidemiology, Biometry and Demography, National Institute of Aging, National Institutes of Health, Bethesda, Maryland.
    Search for more papers by this author
  • Lisa Weissfeld PhD,

    1. From the *Department of Dental Public Health, Division of Geriatric Medicine, Department of Biostatistics, §Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PennsylvaniaDepartment of Preventive Medicine, Health Science Center, University of Tennessee, Memphis, TennesseePrevention Sciences Group, University of California at San Francisco, San Francisco, California#Laboratory of Epidemiology, Biometry and Demography, National Institute of Aging, National Institutes of Health, Bethesda, Maryland.
    Search for more papers by this author
  • Susan M. Rubin MPH,

    1. From the *Department of Dental Public Health, Division of Geriatric Medicine, Department of Biostatistics, §Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PennsylvaniaDepartment of Preventive Medicine, Health Science Center, University of Tennessee, Memphis, TennesseePrevention Sciences Group, University of California at San Francisco, San Francisco, California#Laboratory of Epidemiology, Biometry and Demography, National Institute of Aging, National Institutes of Health, Bethesda, Maryland.
    Search for more papers by this author
  • Tamara Harris MD, MS

    1. From the *Department of Dental Public Health, Division of Geriatric Medicine, Department of Biostatistics, §Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PennsylvaniaDepartment of Preventive Medicine, Health Science Center, University of Tennessee, Memphis, TennesseePrevention Sciences Group, University of California at San Francisco, San Francisco, California#Laboratory of Epidemiology, Biometry and Demography, National Institute of Aging, National Institutes of Health, Bethesda, Maryland.
    Search for more papers by this author

  • This research was funded by National Institutes of Health Grants N01-AG-6–2103, N01-AG-6–2106, and N01-AG-6–210.

Address correspondence to Robert J. Weyant, DMD, DrPH, Department of Dental Public Health, 3501 Terrace St. Room 346, University of Pittsburgh, Pittsburgh, Pennsylvania 15261. E-mail: rjw1@pitt.edu

Abstract

Objectives: To determine the association between periodontal disease and weight loss in an elderly cohort.

Design: A longitudinal design was used with participants from the Health, Aging and Body Composition (Health ABC) cohort study to determine the association between periodontal disease status and weight loss of at least 5% of baseline body weight over a period of 2 years.

Setting: Participants were examined in research clinics in Pittsburgh, Pennsylvania, and Memphis, Tennessee.

Participants: A randomly selected subset of 1,053 individuals from the Health ABC examination, aged 65 and older, ambulatory and community-dwelling at baseline.

Measurements: Periodontal disease was measured as mean pocket depth and attachment loss, extent (percentage) of pockets with at least 6 mm probing depth, extent of bleeding on probing, and tissue inflammation.

Results: In logistic regression models adjusting for variables that may explain weight loss, extent of periodontal pockets with at least 6 mm probing depth showed a significant association with weight loss (odds ratio=1.53, 95% confidence interval=1.32–1.77).

Conclusion: Periodontal disease may be causally related to weight loss in the elderly and thus may increase risk of morbidity and mortality.

Ancillary