A Multifactorial Intervention Program Reduces the Duration of Delirium, Length of Hospitalization, and Mortality in Delirious Patients
Article first published online: 30 MAR 2005
DOI: 10.1111/j.1532-5415.2005.53210.x
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How to Cite
Lundström, M., Edlund, A., Karlsson, S., Brännström, B., Bucht, G. and Gustafson, Y. (2005), A Multifactorial Intervention Program Reduces the Duration of Delirium, Length of Hospitalization, and Mortality in Delirious Patients. Journal of the American Geriatrics Society, 53: 622–628. doi: 10.1111/j.1532-5415.2005.53210.x
Publication History
- Issue published online: 30 MAR 2005
- Article first published online: 30 MAR 2005
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Keywords:
- delirium;
- intervention;
- multifactorial;
- length of hospitalization;
- mortality
Objectives: To investigate whether an education program and a reorganization of nursing and medical care improved the outcome for older delirious patients.
Design: Prospective intervention study.
Setting: Department of General Internal Medicine, Sundsvall Hospital, Sweden.
Participants: Four hundred patients, aged 70 and older, consecutively admitted to an intervention or a control ward.
Intervention: The intervention consisted of staff education focusing on the assessment, prevention, and treatment of delirium and on caregiver-patient interaction. Reorganization from a task-allocation care system to a patient-allocation system with individualized care.
Measurements: The patients were assessed using the Organic Brain Syndrome Scale and the Mini-Mental State Examination on Days 1, 3, and 7 after admission. Delirium was diagnosed according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, criteria.
Results: Delirium was equally common on the day of admission at the two wards, but fewer patients remained delirious on Day 7 on the intervention ward (n=19/63, 30.2% vs 37/62, 59.7%, P=.001). The mean length of hospital stay±standard deviation was significantly lower on the intervention ward then on the control ward (9.4±8.2 vs 13.4±12.3 days, P<.001) especially for the delirious patients (10.8±8.3 vs 20.5±17.2 days, P<.001). Two delirious patients in the intervention ward and nine in the control ward died during hospitalization (P=.03).
Conclusion: This study shows that a multifactorial intervention program reduces the duration of delirium, length of hospital stay, and mortality in delirious patients.

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