Association Between Body Mass Index and Mortality in an 80-Year-Old Population

Authors

  • Yutaka Takata MD, PhD,

    1. From the Divisions of *General Internal MedicineCommunity Oral Health Science, Department of Health Promotion, Kyushu Dental College, Kitakyushu, Japan.
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  • Toshihiro Ansai DDS, PhD,

    1. From the Divisions of *General Internal MedicineCommunity Oral Health Science, Department of Health Promotion, Kyushu Dental College, Kitakyushu, Japan.
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  • Inho Soh DDS, PhD,

    1. From the Divisions of *General Internal MedicineCommunity Oral Health Science, Department of Health Promotion, Kyushu Dental College, Kitakyushu, Japan.
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  • Sumio Akifusa DDS, PhD,

    1. From the Divisions of *General Internal MedicineCommunity Oral Health Science, Department of Health Promotion, Kyushu Dental College, Kitakyushu, Japan.
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  • Kazuo Sonoki MD, PhD,

    1. From the Divisions of *General Internal MedicineCommunity Oral Health Science, Department of Health Promotion, Kyushu Dental College, Kitakyushu, Japan.
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  • Kiyoshi Fujisawa MD,

    1. From the Divisions of *General Internal MedicineCommunity Oral Health Science, Department of Health Promotion, Kyushu Dental College, Kitakyushu, Japan.
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  • Shuji Awano DDS, PhD,

    1. From the Divisions of *General Internal MedicineCommunity Oral Health Science, Department of Health Promotion, Kyushu Dental College, Kitakyushu, Japan.
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  • Shuntaro Kagiyama MD, PhD,

    1. From the Divisions of *General Internal MedicineCommunity Oral Health Science, Department of Health Promotion, Kyushu Dental College, Kitakyushu, Japan.
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  • Tomoko Hamasaki DDS, PhD,

    1. From the Divisions of *General Internal MedicineCommunity Oral Health Science, Department of Health Promotion, Kyushu Dental College, Kitakyushu, Japan.
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  • Ikuo Nakamichi MD, PhD,

    1. From the Divisions of *General Internal MedicineCommunity Oral Health Science, Department of Health Promotion, Kyushu Dental College, Kitakyushu, Japan.
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  • Akihiro Yoshida DDS, PhD,

    1. From the Divisions of *General Internal MedicineCommunity Oral Health Science, Department of Health Promotion, Kyushu Dental College, Kitakyushu, Japan.
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  • Tadamichi Takehara DDS, PhD

    1. From the Divisions of *General Internal MedicineCommunity Oral Health Science, Department of Health Promotion, Kyushu Dental College, Kitakyushu, Japan.
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Address correspondence to Dr. Yutaka Takata, Division of General Internal Medicine, Kyushu Dental College, Manazuru 2-6-1, Kokurakita-ku, Kitakyushu City 803–8580, Japan. E-mail: yutaka@kyu-dent.ac.jp

Abstract

OBJECTIVES: To evaluate the association between body mass index (BMI) and all-cause mortality and cardiovascular disease (CVD) in an 80-year-old population.

DESIGN: Cohort study.

SETTING: Community-based.

PARTICIPANTS: Six hundred ninety-seven of 1,282 (54.4%) 80-year-old candidate individuals.

MEASUREMENTS: The dates and causes of all deaths were followed up for 4 years.

RESULTS: The relative hazard ratios (HRs) for all-cause mortality were lower in overweight subjects (BMI≥25.0) than in underweight (BMI<18.5) or normal-weight (BMI 18.5–24.9) subjects. Similarly, the HRs for mortality due to CVD in overweight subjects were 78% less (HR=0.22, 95% confidence interval (CI)=0.06–0.77) than those in underweight subjects, and those in normal weight subjects were 78% less (HR=0.22, 95% CI=0.08–0.60) than those in underweight subjects. Mortality due to CVD was 4.6 times (HR 4.64, 95% CI=1.68–12.80) as high in underweight subjects as in normal-weight subjects, and mortality due to cancers was 88% lower (HR=0.12, 95% CI=0.02–0.78) in the overweight group than in the underweight group. There were no differences in mortality due to pneumonia.

CONCLUSION: Overweight status was associated with longevity and underweight with short life, due to lower and higher mortality, respectively, from CVD and cancer.

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