Sustained Benzodiazepine Use in a Community Sample of Older Adults
Version of Record online: 15 OCT 2008
© 2008, Copyright the Authors. Journal compilation © 2008, The American Geriatrics Society
Journal of the American Geriatrics Society
Volume 56, Issue 12, pages 2285–2291, December 2008
How to Cite
Stowell, K. R., Chang, C.-C. H., Bilt, J., Stoehr, G. P. and Ganguli, M. (2008), Sustained Benzodiazepine Use in a Community Sample of Older Adults. Journal of the American Geriatrics Society, 56: 2285–2291. doi: 10.1111/j.1532-5415.2008.02011.x
- Issue online: 2 DEC 2008
- Version of Record online: 15 OCT 2008
OBJECTIVES: To identify factors associated with sustained benzodiazepine use in older adults.
DESIGN: Twelve-year cohort study.
SETTING: Community-based epidemiological survey.
PARTICIPANTS: One thousand three hundred forty-two individuals aged 65 and older.
MEASUREMENTS: Demographics, medication use, depressive symptoms, sleep complaints, alcohol use, and smoking assessed at 2-year intervals; descriptive analysis to characterize benzodiazepine users and identify factors associated with sustained benzodiazepine use (use at two consecutive waves); and longitudinal lag-time analysis to determine characteristics that predicted sustained use.
RESULTS: Initially, 5.5% of men and 9.8% of women were using benzodiazepines. Users were significantly more likely than nonusers to be female and less educated, report more depressive and anxiety symptoms, use more prescription medications, have lower self-rated health, have difficulty maintaining sleep, and be less likely to consume alcohol. Approximately 50%, 44%, and 25% of these users aged 65 to 74, 75 to 84, and 85 and older, respectively, were sustained users at follow-up. Being female, using two or more nonbenzodiazepine prescription medications, and smoking were independently associated with subsequent sustained benzodiazepine use.
CONCLUSION: At the population level, women, smokers, and users of at least two prescription drugs have higher probabilities of sustaining benzodiazepine use once started. This information can facilitate risk assessment and counseling of older adults before prescribing benzodiazepines.