This trial was registered on http://www.trialregister.nl (candidate number 1660, NTR number NTR476, ISRCTN29617677, date ISRCTN created 27-jan-2006).
Short-Term Oral Nutritional Intervention with Protein and Vitamin D Decreases Falls in Malnourished Older Adults
Article first published online: 8 FEB 2012
© 2012, Copyright the Authors Journal compilation © 2012, The American Geriatrics Society
Journal of the American Geriatrics Society
Volume 60, Issue 4, pages 691–699, April 2012
How to Cite
Neelemaat, F., Lips, P., Bosmans, J. E., Thijs, A., Seidell, J. C. and van Bokhorst-de van der Schueren, M. A. E. (2012), Short-Term Oral Nutritional Intervention with Protein and Vitamin D Decreases Falls in Malnourished Older Adults. Journal of the American Geriatrics Society, 60: 691–699. doi: 10.1111/j.1532-5415.2011.03888.x
Oral and poster presentation at the ESPEN 2011 congres (Göteborg – Sweden).
- Issue published online: 11 APR 2012
- Article first published online: 8 FEB 2012
- Netherlands Organisation for Health Research and Development
- elderly patients;
- nutritional intervention;
- vitamin D;
To evaluate the effects of a short-term nutritional intervention with protein and vitamin D on falls in malnourished older adults.
Randomized controlled trial.
From hospital admission until 3 months after discharge.
Malnourished older adults (≥60) newly admitted to an acute hospital (n = 210).
Participants were randomized to receive nutritional intervention (energy- and protein-enriched diet, oral nutritional supplements, calcium-vitamin D supplement, telephone counseling by a dietitian) for 3 months after discharge or usual care.
Number of participants who fell, fall incidents, serum 25-hydroxyvitamin D, and dietary intake. Measurements were performed on admission to hospital and 3 months after discharge.
Three months after discharge, 10 participants (10%) in the intervention group had fallen at least once, compared with 24 (23%) in the control group (hazard ratio = 0.41, 95% confidence interval (CI) = 0.19–0.86). There were 57 fall incidents (16 in the intervention group; 41 in the control group). A significantly higher intake of energy (280 kcal, 95% CI = 37–524 kcal) and protein (11 g, 95% CI = 1–25 g) and significantly higher serum 25-hydroxyvitamin D levels (10.9 nmol/L, 95% CI = 2.9–18.9 nmol/L) were found in participants in the intervention group than in controls.
A short-term nutritional intervention consisting of oral nutritional supplements and calcium and vitamin D supplementation and supported by dietetic counseling in malnourished older adults decreases the number of patients who fall and fall incidents.