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Extensive sibling conflict is predictive of multiple poor adjustment outcomes during adolescence and early adulthood, but the frequency and developmental impact of such conflict may be conditional on ineffective parenting. Thus, sibling conflict may add to or amplify the negative effects of ineffective parenting on adolescent boys' adjustment. Hypotheses in this study were that: (a) multiple informant measures of problematic parent–child relationships and of sibling conflict would form distinct constructs rather than a single negative family process construct, and (b) ineffective parenting, sibling conflict, and their interaction measured at ages 10 to 12 would predict boys' concurrent status and developmental trajectories for antisocial behavior and peer adjustment across a 4-year span from ages 12 to 16. Confirmatory factor and latent growth modeling analyses were consistent with these hypotheses, demonstrating the important developmental impact of sibling conflict.