This study was supported in part by the National Institutes of Health-NIAMS, Arthritis Foundation, and the University of Wisconsin-Madison Companion Animal Fund.
Associations Between Canine Juvenile Weight Gain and Coxofemoral Joint Laxity at 16 Weeks of Age
Article first published online: 5 APR 2006
Volume 35, Issue 3, pages 214–218, April 2006
How to Cite
LOPEZ, M. J., QUINN, M. M. and MARKEL, M. D. (2006), Associations Between Canine Juvenile Weight Gain and Coxofemoral Joint Laxity at 16 Weeks of Age. Veterinary Surgery, 35: 214–218. doi: 10.1111/j.1532-950X.2006.00139.x
Dr. Lopez's current address is Laboratory for Equine and Comparative Orthopedic Research, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA.
- Issue published online: 5 APR 2006
- Article first published online: 5 APR 2006
- Submitted July 2005; Accepted October 2005
Objective— Evaluation of the relationship between canine weight gain from 6 to 15 weeks of age and passive coxofemoral joint (CFJ) laxity at 16 weeks of age.
Study Design— Longitudinal cohort study.
Animals— Full- or half-sibling hounds (n=56).
Methods— Hounds were weighed weekly from 6 to 15 weeks of age. Individual average daily gain (ADG) was calculated for each week (weekly) and for the study (overall). PennHIP distraction index (DI) was determined for each CFJ at 16 weeks. Mixed effects linear models were evaluated for associations of DI (highest and mean) with 15-week weight and ADGs (actual or normalized). Left and right DIs were compared with a Student's paired t-test. Significance was set at P<.05. Trends were considered at P<.10.
Results— Mean (±SD) 16-week DI score and 15-week weight was 0.67±0.16 and 12.5±1.8 kg, respectively. Within animal left and right DIs were not significantly different. There were no significant associations between DI and any of the weight gains evaluated. There was a trend for a negative relationship between normalized 14-week ADG and DI in one statistical model.
Conclusions— Weight gain from 6 to 15 weeks of age was unrelated to 16-week PennHIP DI in a homogenous canine population with moderate-to-severe CFJ joint laxity.
Clinical Relevance— Based on our results, ad libitum feeding between 6 and 15 weeks of age does not appear to have an adverse impact on joint laxity at 16 weeks of age as measured by the PennHIP DI.