Esophageal Dysfunction in Dogs with Idiopathic Laryngeal Paralysis: A Controlled Cohort Study
Article first published online: 3 FEB 2010
© Copyright 2010 by The American College of Veterinary Surgeons
Volume 39, Issue 2, pages 139–149, February 2010
How to Cite
STANLEY, B. J., HAUPTMAN, J. G., FRITZ, M. C., ROSENSTEIN, D. S. and KINNS, J. (2010), Esophageal Dysfunction in Dogs with Idiopathic Laryngeal Paralysis: A Controlled Cohort Study. Veterinary Surgery, 39: 139–149. doi: 10.1111/j.1532-950X.2009.00626.x
- Issue published online: 3 FEB 2010
- Article first published online: 3 FEB 2010
- Submitted March 2009; Accepted June 2009
Objectives— To compare esophageal function in dogs with idiopathic laryngeal paralysis (ILP) to age and breed matched controls; to determine if dysfunction is associated with aspiration pneumonia over 1 year; and to compare clinical neurologic examination of dogs with ILP at enrollment and at 1 year.
Study Design— Prospective controlled cohort study.
Animals— Dogs with ILP (n=32) and 34 age and breed matched healthy dogs.
Methods— Mean esophageal score was determined for each phase of 3 phase esophagrams, analyzed blindly. After unilateral cricoarytenoid laryngoplasty, dogs with ILP were reexamined (including thoracic radiography) at 1, 3, 6, and 12 months. Neurologic status was recorded at enrollment, 6 and 12 months.
Results— Esophagram scores in dogs with ILP were significantly higher in each phase compared with controls, most notably with liquid (P<.0001). Dysfunction was more pronounced in the cervical and cranial thoracic esophagus. Five dogs that had aspiration pneumonia during the study had significantly higher esophagram scores than dogs that did not develop aspiration pneumonia (P<.02). Ten (31%) ILP dogs had generalized neurologic signs on enrollment and all ILP dogs developed neurologic signs by 1 year (P<.0001).
Conclusions— Dogs with ILP also have esophageal dysfunction. Postoperative aspiration pneumonia is more likely in dogs with higher esophagram scores. Dogs with ILP will most likely develop generalized neuropathy over the course of 1 year.
Clinical Relevance— Esophagrams and neurologic examinations should be performed on all dogs with ILP.