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In Vitro Comparison of Mechanical and Degradation Properties of Equivalent Absorbable Suture Materials from Two Different Manufacturers


  • Research performed at the Royal Veterinary College, London.

Corresponding Author
Benito de la Puerta, DVM, Cert SAS Diplomate ECVS, North Downs Specialist Referrals, The Friesian Building, The Brewerstreet Diary Business Park, Brewerstreet, Bletchingley, Surrey RH1 4QP, UK


Objective: To compare the mechanical, knotting, and absorption properties of 3 synthetic absorbable suture materials (polyglactin 910, polydioxanone, poliglecaprone 25) from 2 different manufacturers (Huaiyin Medical Instruments Co. Ltd. and Ethicon Inc.).

Sample Population: Suture material samples from the same manufacturing lot for each suture type and manufacturer.

Methods: Part 1: 10 samples of each suture were incubated in bovine serum and tested for ultimate load and stiffness at days 0, 1, 7, 14, 21, and 28. Part 2: 10 knotted samples were similarly evaluated, without incubation.

Results: Huaiyin polydioxanone had a greater (P<.001) ultimate load on days 0, 1, and 7; and a consistently greater stiffness for the duration of the study, compared with the Ethicon polydioxanone. Ethicon poliglecaprone 25 had a greater ultimate load on days 0, 1, 7 (P<.001); on day 21 Huaiyin had a greater ultimate load. Ethicon poliglecaprone had greater stiffness on days 0, 1, 7 (P<.001). Ethicon polyglactin 910 had a greater (P<.001) ultimate load at all times and a greater stiffness (P<.001) at days 0, 1, 7, and 14 compared with Huaiyin polyglactin 910. Huaiyin polydioxanone and polyglactin 910 had greater knot breaking strengths than Ethicon equivalents (P<.001).

Conclusion: Differences in mechanical properties exist between nominally identical suture materials from different manufacturers.