Presented in part at the Veterinary Orthopedic Society meeting, February 20–27, 2010, Breckinridge, CO.
Original Article - Clinical
Evaluation of Topical Epidural Analgesia Delivered in Gelfoam for Postoperative Hemilaminectomy Pain Control
Article first published online: 5 DEC 2012
© Copyright 2012 by The American College of Veterinary Surgeons
Volume 42, Issue 1, pages 79–84, January 2013
How to Cite
Barker, J. R., Clark-Price, S. C. and Gordon-Evans, W. J. (2013), Evaluation of Topical Epidural Analgesia Delivered in Gelfoam for Postoperative Hemilaminectomy Pain Control. Veterinary Surgery, 42: 79–84. doi: 10.1111/j.1532-950X.2012.01082.x
- Issue published online: 3 JAN 2013
- Article first published online: 5 DEC 2012
- Manuscript Accepted: SEP 2011
- Manuscript Received: JUL 2010
To evaluate efficacy of a topical epidural analgesia used alone, or in combination with hydromorphone, against a standard pain protocol for the 48 hours immediately after hemilaminectomy.
Randomized, blinded, controlled, clinical trial.
Dogs (n = 30) with thoracolumbar intervertebral disc disease treated with hemilaminectomy.
Dogs were randomly divided into 3 groups: group 1 received intermittent hydromorphone postoperatively, group 2 received a topical epidural of preservative-free morphine and dexmedetomidine administered via gel foam, group 3 received both forms of analgesia. All dogs were monitored and assessed for pain for 48 hours immediately postoperatively. Data were analyzed using MANOVA and Wilcoxon Rank Sum Tests.
There was a significant temporal difference in treatment groups 1 and 3 when using a 0–10 pain scale (MANOVA, P = .02). There was also a significant difference at the 48th hour postoperatively between groups 1 and 3 (Wilcoxon Rank Sum Test).
Topical epidural of preservative-free morphine and dexmedetomidine administered via gelfoam is not sufficient analgesia alone post hemilaminectomy but in conjunction with other opioid administration may lead to superior pain relief.