Presented in part at the Veterinary Endoscopic Society Meeting March 24, 2012, Park City, UT.
Original Article – Research
Ex Vivo Evaluation of Canine Lung Biopsy Techniques†
Article first published online: 21 FEB 2013
© Copyright 2013 by The American College of Veterinary Surgeons
Volume 42, Issue 4, pages 473–477, May 2013
How to Cite
Marvel, S. and Monnet, E. (2013), Ex Vivo Evaluation of Canine Lung Biopsy Techniques. Veterinary Surgery, 42: 473–477. doi: 10.1111/j.1532-950X.2013.01108.x
- Issue published online: 15 MAY 2013
- Article first published online: 21 FEB 2013
- Manuscript Accepted: 1 NOV 2012
- Manuscript Received: 1 JUN 2012
An ex vivo comparison of thoracoscopic lung biopsy techniques in dogs.
Cadaveric canine lung lobes.
Lungs were inflated to 10 cmH2O. After collecting biopsies 3 cm from the edge of lung lobes, leak pressures were recorded as inflation pressure was increased to 40 cmH2O. Pre-tied loop ligature, square knot (SQ), modified 4S Roeder knot (M4SR) with glycomer 631 and polyglactin 910 size 0 and 2-0 were used in addition to EndoGIA 45–2.5 mm (Covidien, Norwalk, CT) and a vessel sealant device (VSDS single and VSDD double seal). Six biopsies were performed with each of these modalities.
Median airway pressure at which leakage occurred was 28 (20–34) cmH2O for EndoGIA 45; 33 (14–40) for VSDD; and 33 (10–40) for VSDS while other groups reached a median pressure of 40 cmH2O (P < .0001). Leakage occurred at 20 cmH2O in 1 sample with the EndoGIA and the VSDS, and in 2 with the VSDD while leakage did not occur in any other group (P = .36). Leakage occurred at 30 cmH2O in 1 specimen each of the 0-polyglactin SQ, 2-0 glycomer 631 M4SR, 2-0 polyglactin M4SR, and 2-0 Surgitie (Covidien, Norwalk, CT); 2 with the VSDS; and 3 with the EndoGIA and the VSDD while leakage did not occur in any other group (P = .26).
All tested techniques seemed safe except the vessel sealant device since it did not consistently seal every biopsy and leaked at pressures <20 cmH2O.