Association of hyponatremia and hyperglycemia with outcome in dogs with congestive heart failure
Article first published online: 25 AUG 2004
Journal of Veterinary Emergency and Critical Care
Volume 14, Issue 3, pages 177–182, September 2004
How to Cite
Brady, C. A., Hughes, D. and Drobatz, K. J. (2004), Association of hyponatremia and hyperglycemia with outcome in dogs with congestive heart failure. Journal of Veterinary Emergency and Critical Care, 14: 177–182. doi: 10.1111/j.1534-6935.2004.00118.x
- Issue published online: 25 AUG 2004
- Article first published online: 25 AUG 2004
- chronic valvular disease;
- dilated cardiomyopathy;
- plasma glucose;
- plasma sodium
Objective: To evaluate plasma sodium and glucose concentrations in dogs with congestive heart failure (CHF) prior to treatment and evaluate the differences between survivors and non-survivors.
Design: Retrospective study.
Animals: Fifty-nine dogs with CHF prior to receiving cardiac medication.
Measurements and main results: The mean plasma sodium concentration in dogs with CHF was below the reference range (144–156 mmol/L) and significantly lower (P=0.009) in non-survivors (141±6 mmol/L) compared with survivors (147±4 mmol/L). The mean plasma glucose concentration was above the reference range (76–117 mg/dL) and significantly higher (P=0.004) in non-survivors (128±52 mg/dL) compared with survivors (100±13 mg/dL). Forty-four percent of non-survivors had concurrent low plasma sodium and high plasma glucose concentrations, whereas no survivors had both abnormalities (P<0.0001).
Conclusions: Lower plasma sodium and higher plasma glucose are associated with a worse outcome in dogs with CHF.