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Keywords:

  • canine;
  • chronic valvular disease;
  • dilated cardiomyopathy;
  • plasma glucose;
  • plasma sodium

Abstract

Objective: To evaluate plasma sodium and glucose concentrations in dogs with congestive heart failure (CHF) prior to treatment and evaluate the differences between survivors and non-survivors.

Design: Retrospective study.

Animals: Fifty-nine dogs with CHF prior to receiving cardiac medication.

Interventions: None.

Measurements and main results: The mean plasma sodium concentration in dogs with CHF was below the reference range (144–156 mmol/L) and significantly lower (P=0.009) in non-survivors (141±6 mmol/L) compared with survivors (147±4 mmol/L). The mean plasma glucose concentration was above the reference range (76–117 mg/dL) and significantly higher (P=0.004) in non-survivors (128±52 mg/dL) compared with survivors (100±13 mg/dL). Forty-four percent of non-survivors had concurrent low plasma sodium and high plasma glucose concentrations, whereas no survivors had both abnormalities (P<0.0001).

Conclusions: Lower plasma sodium and higher plasma glucose are associated with a worse outcome in dogs with CHF.