Objective: To evaluate plasma sodium and glucose concentrations in dogs with congestive heart failure (CHF) prior to treatment and evaluate the differences between survivors and non-survivors.
Design: Retrospective study.
Animals: Fifty-nine dogs with CHF prior to receiving cardiac medication.
Measurements and main results: The mean plasma sodium concentration in dogs with CHF was below the reference range (144–156 mmol/L) and significantly lower (P=0.009) in non-survivors (141±6 mmol/L) compared with survivors (147±4 mmol/L). The mean plasma glucose concentration was above the reference range (76–117 mg/dL) and significantly higher (P=0.004) in non-survivors (128±52 mg/dL) compared with survivors (100±13 mg/dL). Forty-four percent of non-survivors had concurrent low plasma sodium and high plasma glucose concentrations, whereas no survivors had both abnormalities (P<0.0001).
Conclusions: Lower plasma sodium and higher plasma glucose are associated with a worse outcome in dogs with CHF.