Article first published online: 20 OCT 2009
Volume 3, Issue 2, pages 114–124, March-April 1963
How to Cite
Finn, R., Harper, D. T., Stallings, S. A. and Krevans, J. R. (1963), Transplacental Hemorrhage. Transfusion, 3: 114–124. doi: 10.1111/j.1537-2995.1963.tb05913.x
- Issue published online: 20 OCT 2009
- Article first published online: 20 OCT 2009
- Received for publication August 17, 1962; accepted November 1, 1962.
The development of knowledge concerning the phenomenon of transplacental hemorrhage into the maternal circulation is reviewed, and evidence is presented that the acid elution technic provides a simple and accurate method of diagnosing this condition. The data in the present study suggest that transplacental hemorrhage is not a random phenomenon but is related to obstetric abnormalities and procedures, and the relevance of this finding to the management of the Rh negative unsensitized mother is discussed. It is suggested that the acid elution technic will find useful applications in the diagnosis of neonatal anemia due to massive transplacental hemorrhage, and in the further elucidation of the mechanism of Rh sensitization.