C. R. Valeri, CAPT, MC, USNR, Officer in Charge, Naval Blood Research Laboratory, Chelsea, Mass.
The Relation Between Response to Hypotonic Stress and the 51Cr Recovery In Vivo of Preserved Platelets
Article first published online: 20 OCT 2009
Volume 14, Issue 4, pages 331–337, July-August 1974
How to Cite
Valeri, C. R., Feingold, H. and Marchionni, L. D. (1974), The Relation Between Response to Hypotonic Stress and the 51Cr Recovery In Vivo of Preserved Platelets. Transfusion, 14: 331–337. doi: 10.1111/j.1537-2995.1974.tb04541.x
- Issue published online: 20 OCT 2009
- Article first published online: 20 OCT 2009
- Received for publication August 8, 1973; accepted February 5, 1974.
Platelet response to hypotonic stress can be used to estimate the 51Cr recovery in vivo of liquid- and freeze-preserved platelets. This simple in vitro test may prove helpful in determining and controlling the quality of preserved platelets. In our study, the response to hypotonic stress was not related to the 51Cr T-1/2 value of the preserved platelets, but was related to the number of irreversibly damaged platelets removed within two hours after transfusion.