• 1
    Hemker H, Beguin S. Thrombin generation in plasma: its assessment via the endogenous thrombin potential. Thromb Haemost 1995; 74: 1348.
  • 2
    Butenas S, Van't Veer C, Mann K. ‘Normal’ thrombin generation. Blood 1999; 94: 216978.
  • 3
    Hemker H, Beguin S. Phenotyping the clotting system. Thromb Haemost 2000; 84: 74751.
  • 4
    Mannucci P. The measurement of multifactorial thrombophilia. Thromb Haemost 2002; 88: 12.
  • 5
    Mann K, Brummel K, Butenas S. What is all that thrombin for? J Thromb Haemost 2003; 1: 150414.DOI: 10.1046/j.1538-7836.2003.00298.x
  • 6
    Hemker H, Willems G, Beguin S. A computer assisted method to obtain the prothrombin activation velocity in whole plasma independent of thrombin decay processes. Thromb Haemost 1986; 56: 917.
  • 7
    Hemker H, Wielders S, Kessels H, Beguin S. Continuous registration of thrombin generation in plasma, its use for the determination of the thrombin potential. Thromb Haemost 1993; 70: 61724.
  • 8
    Rand M, Lock J, Van't Veer C, Gaffney D, Mann K. Blood clotting in minimally altered whole blood. Blood 1996; 88: 342245.
  • 9
    Hemker H, Giesen P, Al Dieri R et al. Calibrated automated thrombin generation measurement in clotting plasma. Pathophysiol Haemost Thromb 2003; 33: 415.DOI: 10.1159/000071636
  • 10
    Falls L, Furie B, Furie BC. Role of phosphatidylethanolamine in assembly and function of the factor Ixa–factor VIIIa complex on membrane surfaces. Biochemistry 2000; 39: 132122.
  • 11
    Hemker H, Giesen P, Ramjee M, Wagenvoord R, Beguin S. The thrombogram: monitoring thrombin generation in platelet-rich plasma. Thromb Haemost 2000; 83: 58992.
  • 12
    Josso F, Prou-Wartelle O. Interaction of tissue factor and factor VII at the earliest phase of coagulation. Thromb Diath Haemorrh 1965; 17: 3544.
  • 13
    Osterud B, Rapaport S. Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation. Proc Natl Acad Sci, USA 1977; 74: 52604.
  • 14
    Gailani D, Broze G. Factor XI activation in a revised model of blood coagulation. Science 1991; 253: 90912.
  • 15
    Brummel K, Paradis S, Butenas S, Mann K. Thrombin functions during tissue factor-induced blood coagulation. Blood 2002; 100: 14852.
  • 16
    Silverberg M, Dunn J, Garen L, Kaplan A. Autoactivation of human Hageman factor. Demonstration utilizing a synthetic substrate. J Biol Chem 1980; 255: 72816.
  • 17
    Hong J, Larsson A, Ekdahl K, Elgue G, Larsson R, Nilsson B. Contact between a polymer and whole blood: sequence of events leading to thrombin generation. J Lab Clin Med 2001; 138: 13945.DOI: 10.1067/mlc.2001.116486
  • 18
    Hojima Y, Pierce J, Pisano J. Hageman factor fragment inhibitor in corn seeds: purification and characterisation. Thromb Res 1980; 20: 14962.DOI: 10.1016/0049-3848(80)90381-3
  • 19
    Schneider D, Tracy P, Mann K, Sobel B. Differential effects of anticoagulants on the activation of platelets ex vivo. Circulation 1997; 96: 287783.
  • 20
    Cawthern K, Van't Veer C, Lock J, DiLorenzo M, Branda R, Mann K. Blood coagulation in hemophilia A and hemophilia C. Blood 1998; 91: 458192.
  • 21
    Kumar R, Beguin S, Hemker HC. The influence of fibrinogen and fibrin on thrombin generation—evidence for feedback activation of the clotting system by clot bound thrombin. Thromb Haemost 1994; 72: 71321.
  • 22
    Becker D, Fredenburgh J, Stafford A, Weitz J. Exosites 1 and 2 are essential for protection of fibrin-bound thrombin from heparin-catalyzed inhibition by antithrombin and heparin cofactor II. J Biol Chem 1999; 274: 622633.