• 1
    Chang P, Aronson DL, Borenstein DG, Kessler CM. Coagulant proteins and thrombin generation in synovial fluid: a model for extravascular coagulation. Am J Hematol 1995; 50: 7983.
  • 2
    Le DT, Borgs P, Toneff TW, Witte MH, Rapaport SI. Hemostatic factors in rabbit limb lymph: relationship to mechanisms regulating extravascular coagulation. Am J Physiol 1998; 274: H76976.
  • 3
    Bauer KA, Kass BL, Ten Cate H, Bednarek MA, Hawiger JJ, Rosenberg RD. Detection of factor X activation in humans. Blood 1989; 74: 200715.
  • 4
    Jesty J, Beltrami E. Positive feedbacks of coagulation: their role in threshold regulation. Arterioscler Thromb Vasc Biol 2005; 25: 24639.
  • 5
    Dackiw AP, McGilvray ID, Woodside M, Nathens AB, Marshall JC, Rotstein OD. Prevention of endotoxin-induced mortality by antitissue factor immunization. Arch Surg 1996; 131: 12738; discussion–1278; 9.
  • 6
    Contrino J, Hair GA, Schmeizl MA, Rickles FR, Kreutzer DL. In situ characterization of antigenic and functional tissue factor expression in human tumors utilizing monoclonal antibodies and recombinant factor VIIa as probes. Am J Pathol 1994; 145: 131522.
  • 7
    Contrino J, Hair G, Kreutzer DL, Rickles FR. In situ detection of tissue factor in vascular endothelial cells: correlation with the malignant phenotype of human breast disease. Nat Med 1996; 2: 20915.
  • 8
    Banner DW, D'Arcy A, Chene C, Winkler FK, Guha A, Konigsberg WH, Nemerson Y, Kirchhofer D. The crystal structure of the complex of blood coagulation factor VIIa with human soluble tissue factor. Nature 1996; 380: 416.
  • 9
    Colina C, Venkateswarlu D, Duke R, Perera L, Pedersen L. What causes the enhancement of activity of factor VIIa by tissue factor? J Thromb Haemost 2006; 4: 27269.
  • 10
    Venkateswarlu D, Duke RE, Perera L, Darden TA, Pedersen LG. An all-atom solution-equilibrated model for human extrinsic blood coagulation complex (sTF–VIIa–Xa): a protein–protein docking and molecular dynamics refinement study. J Thromb Haemost 2003; 1: 257788.
  • 11
    Sompuram SR, Vani K, Messana E, Bogen SA. A molecular mechanism of formalin fixation and antigen retrieval. Am J Clin Pathol 2004; 121: 1909.
  • 12
    Drake TA, Morrissey JH, Edgington TS. Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis. Am J Pathol 1989; 134: 108797.
  • 13
    Wilcox JN, Smith KM, Schwartz SM, Gordon D. Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque. Proc Natl Acad Sci USA 1989; 86: 283943.
  • 14
    Fleck RA, Rao LVM, Rapaport SI, Varki N. Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody. Thromb Res 1990; 59: 42137.
  • 15
    Krishnaswamy S. The interaction of human factor VIIa with tissue factor. J Biol Chem 1992; 267: 23696706.
  • 16
    Broze GJ. Binding of human factor VII and VIIa to monocytes. J Clin Invest 1982; 70: 52635.
  • 17
    Wilcox JN, Noguchi S, Casanova J. Extrahepatic synthesis of factor VII in human atherosclerotic vessels. Arterioscler Thromb Vasc Biol 2003; 23: 13641.
  • 18
    Hatton MW, Blajchman MA, Sridhara S, Southward SM, Ross B, Kulzcycky M, Clarke BJ. Metabolism of rabbit plasma-derived factor VII in relation to prothrombin in rabbits. Am J Physiol Endocrinol Metab 2001; 281: E50715.
  • 19
    Rivard GE, Kovac I, Kunschak M, Thone P. Clinical study of recovery and half-life of vapor-heated factor VII concentrate. Transfusion 1994; 34: 9759.
  • 20
    Girolami A, Scarano L, Saggiorato G, Girolami B, Bertomoro A, Marchiori A. Congenital deficiencies and abnormalities of prothrombin. Blood Coagul Fibrinolysis 1998; 9: 55769.
  • 21
    Mariani G, Konkle BA, Ingerslev J. Congenital factor VII deficiency: therapy with recombinant activated factor VII – a critical appraisal. Haemophilia 2006; 12: 1927.
  • 22
    Ruf W, Kelly CR, Schullek JR, Martin DM, Polikarpov I, Boys CW, Tuddenham EG, Edgington TS. Energetic contributions and topographical organization of ligand binding residues of tissue factor. Biochemistry 1995; 34: 63105.
  • 23
    Kelley RF, Yang J, Eigenbrot C, Moran P, Peek M, Lipari MT, Kirchhofer D. Similar molecular interactions of factor VII and factor VIIa with the tissue factor region that allosterically regulates enzyme activity. Biochemistry 2004; 43: 12239.
  • 24
    Huang M, Syed R, Stura EA, Stone MJ, Stefanko RS, Ruf W, Edgington TS, Wilson IA. The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5 G9 and TF.G9 complex. J Mol Biol 1998; 275: 87394.
  • 25
    Ohto U, Mizutani R, Nakamura M, Adachi H, Satow Y. Crystal structure of a humanized Fab fragment of anti-tissue-factor antibody in complex with tissue factor. J Synchrotron Radiat 2004; 11: 1058.
  • 26
    Chen VM, Ahamed J, Versteeg HH, Berndt MC, Ruf W, Hogg PJ. Evidence for activation of tissue factor by an allosteric disulfide bond. Biochemistry 2006; 45: 120208.
  • 27
    Ahamed J, Versteeg HH, Kerver M, Chen VM, Mueller BM, Hogg PJ, Ruf W. Disulfide isomerization switches tissue factor from coagulation to cell signaling. Proc Natl Acad Sci USA 2006; 103: 139327.