• 1
    Ishii H, Umeda F, Hashimoto T, Nawata H. Changes in phosphoinositide turnover, Ca2+ mobilization, and protein phosphorylation in platelets from NIDDM patients. Diabetes 1990; 39: 15618.
  • 2
    Yamaguchi T, Kadono K, Tetsutani T, Yasunaga K. Platelet free Ca2+ concentration in non-insulin-dependent diabetes mellitus. Diabetes Res 1991; 18: 8994.
  • 3
    Tschope D, Rosen P, Gries FA. Increase in the cytosolic concentration of calcium in platelets of diabetics type II. Thromb Res 1991; 62: 4218.
  • 4
    Vicari AM, Taglietti MV, Pellegatta F, Spotti D, Melandri M, Galli L, Ronchi P, Folli F. Deranged platelet calcium homeostasis in diabetic patients with end-stage renal failure. A possible link to increased cardiovascular mortality? Diabetes Care 1996; 19: 10626.
  • 5
    Schaeffer G, Wascher TC, Kostner GM, Graier WF. Alterations in platelet Ca2+ signalling in diabetic patients is due to increased formation of superoxide anions and reduced nitric oxide production. Diabetologia 1999; 42: 16776.
  • 6
    Mazzanti L, Rabini RA, Fumelli P, Martarelli D, Staffolani R, Salvolini E, Curatola G. Altered platelet membrane dynamic properties in type 1 diabetes. Diabetes 1997; 46: 206974.
  • 7
    Li Y, Woo V, Bose R. Platelet hyperactivity and abnormal Ca2+ homeostasis in diabetes mellitus. Am J Physiol Heart Circ Physiol 2001; 280: H14809.
  • 8
    Takaya J, Iwamoto Y, Higashino H, Ishihara R, Kobayashi Y. Increased intracellular calcium and altered phorbol dibutyrate binding to intact platelets in young subjects with insulin-dependent and non-insulin-dependent diabetes mellitus. Metabolism 1997; 46: 94953.
  • 9
    Enouf J, Bobe R, Lacabaratz-Porret C, Bredoux R, Corvazier E, Kovàcs T, Papp B. The platelet Ca2+ transport ATPase system. Platelets 1997; 8: 513.
  • 10
    Bobe R, Bredoux R, Corvazier E, Lacabaratz-Porret C, Martin V, Kovacs T, Enouf J. How many Ca2+ATPase isoforms are expressed in a cell type? A growing family of membrane proteins illustrated by studies in platelets Platelets 2005; 16: 13350.
  • 11
    Dean WL, Quinton TM. Distribution of plasma membrane Ca2+-ATPase and inositol 1,4,5-trisphosphate receptor in human platelet membranes. Cell Calcium 1995; 17: 6570.
  • 12
    Paszty K, Kovàcs T, Lacabaratz-Porret C, Papp B, Enouf J, Filoteo AG, Penniston JT, Enyedi A. Expression of hPMCA4b, the major form of the plasma membrane calcium pump in megakaryoblastoid cells is greatly reduced in mature human platelets. Cell Calcium 1998; 24: 12935.
  • 13
    Martin V, Bredoux R, Corvazier E, Papp B, Enouf J. Platelet Ca2+ATPases: a plural, species-specific, and multiple hypertension-regulated expression system. Hypertension 2000; 35: 91102.
  • 14
    Enouf J, Bredoux R, Papp B, Djaffar I, Lompré AM, Kieffer N, Gayet O, Clemetson K, Wuytack F, Rosa JP. Human platelets express the SERCA2-b isoform of Ca2+-transport ATPase. Biochem J 1992; 286: 13540.
  • 15
    Martin V, Bredoux R, Corvazier E, Gorp Rv, Kovàcs T, Gélébart P, Enouf J. Three novel sarco/endoplasmic reticulum Ca2+ATPase (SERCA) 3 isoforms. Expression, regulation and function of the members of the SERCA3 family. J Biol Chem 2002; 277: 2444252.
  • 16
    Bobe R, Bredoux R, Corvazier E, Andersen JP, Clausen JD, Dode L, Kovàcs T, Enouf J. Identification, expression, function and localization of a novel (sixth) isoform of the human Sarco/Endoplasmic Reticulum Ca2+ATPase 3 (SERCA3) gene. J Biol Chem 2004; 279: 24297306.
  • 17
    Papp B, Corvazier E, Magnier C, Kovàcs T, Bourdeau N, Lévy-Tolédano S, Bredoux R, Lévy B, Poitevin P, Lompré AM, Wuytack F, Enouf J. Spontaneously hypertensive rats and platelet Ca2+-ATPases: specific up-regulation of the 97 kDa isoform. Biochem J 1993; 295: 68590.
  • 18
    Bobe R, Bredoux R, Wuytack F, Quarck R, Kovàcs T, Papp B, Corvazier E, Magnier C, Enouf J. The rat platelet 97-kDa Ca2+ATPase isoform is the sarcoendoplasmic reticulum Ca2+ATPase 3 protein. J Biol Chem 1994; 269: 141724.
  • 19
    Wuytack F, Papp B, Verboomen H, Raeymaekers L, Dode L, Bobe R, Enouf J, Bokkala S, Authi KS, Casteels R. A sarco/endoplasmic reticulum Ca2+ATPase 3-type Ca2+ pump is expressed in platelets, in lymphoid cells, and in mast cells. J Biol Chem 1994; 269: 14106.
  • 20
    Kovàcs T, Felfoldi F, Papp B, Paszty K, Bredoux R, Enyedi A, Enouf J. All three splice variants of the human sarco/endoplasmic reticulum Ca2+ATPase 3 gene are translated to proteins. A study of their co-expression in platelets and lymphoid cells. Biochem J 2001; 358: 55968.
  • 21
    Lacabaratz-Porret C, Launay S, Corvazier E, Bredoux R, Papp B, Enouf J. Biogenesis of endoplasmic reticulum proteins involved in Ca2+ signalling during megakaryocytic differentiation: an in vitro study. Biochem J 2000; 350: 72334.
  • 22
    Bredoux R, Corvazier E, Dally S, Chaabane C, Bobe R, Raies A, Moreau A, Enouf J. Human platelet Ca2+-ATPases: new markers of cell differentiation as illustrated in idiopathic scoliosis. Platelets 2006; 17: 42133.
  • 23
    Nurden P, Debili N, Vainchenker W, Bobe R, Bredoux R, Corvazier E, Combrié R, Fressinaud E, Meyer D, Nurden AT. Impaired megakaryocytopoiesis in type 2B von Willebrand disease with severe thrombocytopenia. Blood 2006; 108: 258795.
  • 24
    Mazzanti L, Rabini RA, Faloia E, Fumelli P, Bertoli E, De Pirro R. Altered cellular Ca2+ and Na+ transport in diabetes mellitus. Diabetes 1990; 39: 8504.
  • 25
    Rosado JA, Saavedra FR, Redondo PC, Hernandez-Cruz JM, Salido GM, Pariente JA. Reduced plasma membrane Ca2+-ATPase function in platelets from patients with non-insulin-dependent diabetes mellitus. Haematologica 2004; 89: 11424.
  • 26
    Varadi A, Lebel L, Hashim Y, Mehta Z, Ashcroft SJ, Turner R. Sequence variants of the sarco(endo)plasmic reticulum Ca2+-transport ATPase 3 gene (SERCA3) in Caucasian type II diabetic patients (UK Prospective Diabetes Study 48). Diabetologia 1999; 42: 12403.
  • 27
    Borge PD Jr, Wolf BA. Insulin receptor substrate 1 regulation of sarco-endoplasmic reticulum calcium ATPase 3 in insulin-secreting β-cells. J Biol Chem 2003; 278: 1135968.
  • 28
    Chaabane C, Corvazier E, Bredoux R, Dally S, Raies A, Villemain A, Dupuy E, Enouf J, Bobe R. Sarco/endoplasmic reticulum Ca2+ATPase type 3 isoforms (SERCA3b and SERCA3f): distinct roles in cell adhesion and ER stress. Biochem Biophys Res Commun 2006; 345: 137785.
  • 29
    Kuang E, Wan Q, Li X, Xu H, Zou T, Qi Y. ER stress triggers apoptosis induced by Nogo-B/ASY overexpression. Exp Cell Res 2006; 312: 19838.
  • 30
    Dally S, Bredoux R, Corvazier E, Andersen JP, Clausen JD, Dode L, Fanchaouy M, Gélébart P, Monceau V, Del Monte F, Gwathmey JK, Hajjar R, Chaabane C, Bobe R, Raies A, Enouf J. Ca2+-ATPases in non-failing and failing heart: evidence for a novel cardiac sarco/endoplasmic reticulum Ca2+ATPase 2 isoform (SERCA2c). Biochem J 2006; 395: 24958.
  • 31
    Dean WL, Chen D, Brandt PC, Vanaman TC. Regulation of platelet plasma membrane Ca2+-ATPase by cAMP-dependent and tyrosine phosphorylation. J Biol Chem 1997; 272: 151139.
  • 32
    Andrews RK, Munday AD, Mitchell CA, Berndt MC. Interaction of calmodulin with the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complex. Blood 2001; 98: 6817.
  • 33
    Andrews RK, Suzuki-Inoue K, Shen Y, Tulasne D, Watson SP, Berndt MC. Interaction of calmodulin with the cytoplasmic domain of platelet glycoprotein VI. Blood 2002; 99: 421921.
  • 34
    Arthur JF, Shen Y, Mu FT, Leon C, Gachet C, Berndt MC, Andrews RK. Calmodulin interacts with the platelet ADP receptor P2Y1. Biochem J 2006; 398: 33943.
  • 35
    Schuh K, Uldrijan S, Telkamp M, Rothlein N, Neyses L. The plasma membrane calmodulin-dependent calcium pump: a major regulator of nitric oxide synthase I. J Cell Biol 2001; 155: 2015.
  • 36
    Williams JC, Armesilla AL, Mohamed TM, Hagarty CL, McIntyre FH, Schomburg S, Zaki AO, Oceandy D, Cartwright EJ, Buch MH, Emerson M, Neyses L. The sarcolemmal calcium pump, alpha-1 syntrophin, and neuronal nitric-oxide synthase are parts of a macromolecular protein complex. J Biol Chem 2006; 281: 233418.
  • 37
    Rimessi A, Coletto L, Pinton P, Rizzuto R, Brini M, Carafoli E. Inhibitory interaction of the 14-3-3{epsilon} protein with isoform 4 of the plasma membrane Ca2+-ATPase pump. J Biol Chem 2005; 280: 37195203.
  • 38
    Roe MW, Philipson LH, Frangakis CJ, Kuznetsov A, Mertz RJ, Lancaster ME, Spencer B, Worley JF III, Dukes ID. Defective glucose-dependent endoplasmic reticulum Ca2+ sequestration in diabetic mouse islets of Langerhans. J Biol Chem 1994; 269: 1827982.
  • 39
    Varadi A, Molnar E, Ostenson C-G, Ashcroft SJH. Isoforms of endoplasmic reticulum Ca2+-ATPase are differentially expressed in normal and diabetic islet of Langerhans. Biochem J 1996; 319: 5217.
  • 40
    Jonas J-C SA, Hasenkamp W, Ilkova H, Patané G, Laybutt R, Bonner-Weir S, Weir G. Chronic hyperglycemia triggers loss of pancreatic β cell differentiation in an animal model of diabetes. J Biol Chem 1999; 274: 1411221.
  • 41
    Xu GG, Gao Z, Borge PD Jr, Jegier PA, Young RA, Wolf BA. Insulin regulation of beta-cell function involves a feedback loop on SERCA gene expression, Ca2+ homeostasis, and insulin expression and secretion. Biochemistry 2000; 39: 149129.
  • 42
    Kulkarni RN, Roper MG, Dahlgren G, Shih DQ, Kauri LM, Peters JL, Stoffel M, Kennedy RT. Islet secretory defect in insulin receptor substrate 1 null mice is linked with reduced calcium signaling and expression of Sarco(endo)plasmic Reticulum Ca2+-ATPase (SERCA)-2b and -3. Diabetes 2004; 53: 151725.
  • 43
    Watanabe Y, Kawada M, Kobayashi B. Effect of insulin on murine megakaryocytopoiesis in a liquid culture system. Cell Struct Funct 1987; 12: 3116.
  • 44
    Tschope D, Schwippert B, Schettler B, Kiesel U, Rothe H, Roesen P, Gries FA. Increased GPIIB/IIIA expression and altered DNA-ploidy pattern in megakaryocytes of diabetic BB-rats. Eur J Clin Invest 1992; 22: 5918.
  • 45
    Brown AS, Hong Y, De Belder A, Beacon H, Beeso J, Sherwood R, Edmonds M, Martin JF, Erusalimsky JD. Megakaryocyte ploidy and platelet changes in human diabetes and atherosclerosis. Arterioscler Thromb Vasc Biol 1997; 17: 8027.
  • 46
    Hekimsoy Z, Payzin B, Ornek T, Kandogan G. Mean platelet volume in Type 2 diabetic patients. J Diabetes Complicat 2004; 18: 1736.
  • 47
    Watala C, Boncler M, Gresner P. Blood platelet abnormalities and pharmacological modulation of platelet reactivity in patients with diabetes mellitus. Pharmacol Rep 2005; 57: 4258.