• 1
    White RH.. The epidemiology of venous thromboembolism. Circulation 2003; 107: I-4I-8.
  • 2
    Anderson FA, Wheeler HB, Goldberg RJ, Hosmer DW, Patwardhan NA, Jovanovic B, Forcier A, Dalen JE. A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. Arch Intern Med 1991; 151: 9338.
  • 3
    Silverstein MD, Heit JA, Mohr DN, Petterson TM, O’Fallen WM, Melton J. Trends in the incidence of deep vein thrombosis and pulmonary embolism. Arch Intern Med 1998; 158: 58593.
  • 4
    White RH, Zhou H, Romano PS. Incidence of idiopathic deep venous thrombosis and secondary thromboembolism among ethnic groups in California. Ann Intern Med 1998; 128: 73740.
  • 5
    Fowkes FJ, Price JF, Fowkes FG. Incidence of diagnosed deep vein thrombosis in the general population: systematic review. Eur J Vasc Endovasc Surg 2003; 25: 15.
  • 6
    Moores L, Bilello KL, Murin S. Sex and gender issues and venous thromboembolism. Clin Chest Med 2004; 25: 28197.
  • 7
    Romero A, Alonso C, Rincon M, Medrano J, Santos JM, Calderon E, Marin I, Gonzalez MA. Risk of venous thromboembolic disease in women A qualitative systematic review. Eur J Obstet Gynecol Reprod Biol 2005; 121: 817.
  • 8
    Huisman MV, Buller HR, Ten Cate JW, Vreeken J. Serial impedance plethysmography for suspected deep venous thrombosis in outpatients. The Amsterdam General Practitioner Study. N Engl J Med 1986; 314: 8238.
  • 9
    Heijboer H, Buller HR, Lensing AWA, Turpie AGG, Colly LP, Ten Cate WJ. A comparison of real-time compression ultrasonography with impedance plethysmography for the diagnosis of deep-vein thrombosis in symptomatic outpatients. N Engl J Med 1993; 329: 13659.
  • 10
    Wells PS, Anderson DR, Bormanis J, Guy F, Mitchell M, Gray L, Clement C, Robinson KS, Lewandowski B. Value of assessment of pretest probability of deep-vein thrombosis in clinical management. Lancet 1997; 350: 17958.
  • 11
    Cogo A, Lensing AWA, Koopman MMW, Piovella F, Siragusa S, Wells PS, Villalta S, Buller HR, Turpie AGG, Prandoni P. Compression ultrasonography for diagnostic management of patients with clinically suspected deep vein thrombosis: prospective cohort study. Br Med 1998; 316: 1720.
  • 12
    Bernardi E, Prandoni P, Lensing AWA, Agnelli G, Guazzaloca G, Scannapieco G, Piovella F. D-dimer testing as an adjunct to ultrasonography in patients with clinically suspected deep vein thrombosis: prospective cohort study. Br Med J 1998; 317: 103740.
  • 13
    Tick LW, Ton E, Van Voorthuizen T, Hovens MM, Leeuwenburgh I, Lobatto S, Stijnen PJ, Van Der HC, Huisman PM, Kramer MH, Huisman MV. Practical diagnostic management of patients with clinically suspected deep vein thrombosis by clinical probability test, compression ultrasonography, and D-dimer test. Am J Med 2002; 113: 6305.
  • 14
    Anderson DR, Kovacs MJ, Kovacs G, Stiell I, Mitchell M, Khoury V, Dryer J, Ward J, Wells PS. Combined use of clinical assessment and d-dimer to improve the management of patients presenting to the emergency department with suspected deep vein thrombosis (the EDITED Study). J Thromb Haemost 2003; 1: 64551.
  • 15
    Wells PS, Anderson DR, Rodger M, Forgie M, Kearon C, Dreyer J, Kovacs G, Mitchell M, Lewandowski B, Kovacs MJ. Evaluation of D-dimer in the diagnosis of suspected deep-vein thrombosis. N Eng J Med 2003; 349: 122735.
  • 16
    Oudega R, Hoes AW, Moons KG. The Wells rule does not adequately rule out deep venous thrombosis in primary care patients. Ann Intern Med 2005; 143: 1007.
  • 17
    Beebe HG, Scissons RP, Salles-Cunha SX, Dosick SM, Whalen RC, Gale SS, Pigott JP, Vitti MJ. Gender bias in use of venous ultrasonography for diagnosis of deep venous thrombosis. J Vasc Surg 1995; 22: 53842.
  • 18
    Wells PS, Owen C, Doucette S, Fergusson D, Tran H. Does this patient have deep vein thrombosis? JAMA 2006; 295: 199207.
  • 19
    Goodacre S, Sutton AJ, Sampson FC. Meta-analysis: the value of clinical assessment in the diagnosis of deep venous thrombosis. Ann Intern Med 2005; 143: 12939.
  • 20
    Qaseem A, Snow V, Barry P, Hornbake ER, Rodnick JE, Tobolic T, Ireland B, Segal JB, Bass EB, Weiss KB, Green L, Owens DK. Current diagnosis of venous thromboembolism in primary care: a clinical practice guideline from the American Academy of Family Physicians and the American College of Physicians. Ann Intern Med 2007; 146: 4548.
  • 21
    Kearon C, Ginsberg JS, Douketis J, Crowther M, Brill-Edwards P, Weitz JI, Hirsh J. Management of suspected deep venous thrombosis in outpatients by using clinical assessment and D-dimer testing. Ann Intern Med 2001; 135: 10811.
  • 22
    Bates SM, Kearon C, Crowther M, Linkins L, O’Donnell M, Douketis J, Lee AY, Weitz JI, Johnston M, Ginsberg JS. A diagnostic strategy involving a quantitative latex D-dimer assay reliably excludes deep venous thrombosis. Ann Intern Med 2003; 138: 78794.
  • 23
    Kearon C, Ginsberg JS, Douketis J, Crowther MA, Turpie AG, Bates SM, Lee A, Brill-Edwards P, Finch T, Gent M. A randomized trial of diagnostic strategies after normal proximal vein ultrasonography for suspected deep venous thrombosis: D-dimer testing compared with repeated ultrasonography. Ann Intern Med 2005; 142: 4906.
  • 24
    Altman DG, Bland JM. Interaction revisited: the difference between two estimates. Br Med J 2003; 326: 219.
  • 25
    Kahn SR, Joseph L, Abenhaim L, Leclerc JR. Clinical prediction of deep vein thrombosis in patients with leg symptoms. Thromb Haemost 1999; 81: 3537.
  • 26
    Oudega R, Moons KG, Hoes AW. Limited value of patient history and physical examination in diagnosing deep vein thrombosis in primary care. Fam Pract 2005; 22: 8691.
  • 27
    Kraaijenhagen RA, Piovella F, Bernardi E, Verlato F, Beckers EA, Koopman MM, Barone M, Camporese G, Potter Van Loon BJ, Prins MH, Prandoni P, Buller HR. Simplification of the diagnostic management of suspected deep vein thrombosis. Arch Intern Med 2002; 162: 90711.
  • 28
    Stevens SM, Elliott CG, Chan KJ, Egger MJ, Ahmed KM. Withholding anticoagulation after a negative result on duplex ultrasonography for suspected symptomatic deep venous thrombosis. Ann Intern Med 2004; 140: 98591.
  • 29
    McRae S, Tran H, Schulman S, Ginsberg J, Kearon C. Effect of patient’s sex on risk of recurrent venous thromboembolism: a meta-analysis. Lancet 2006; 368: 3718.