- Top of page
- MI/CAD risk loci
- QTLs for platelet phenotypes
- The Cambridge HaemAtlas
- Zebrafish as model organism for fast screening of novel candidate genes
- Future developments
- Disclosure of Conflict of Interests
Summary. The era of Genome-Wide Association Studies (GWAS) commenced in 2007 with the study of the Wellcome Trust Case Control Consortium (WTCCC) which for the first time ever showed that risk loci can be identified by scanning the complete genome for sequence variation in large numbers of cases of disease and healthy controls. We and others have expanded on this effort and successfully identified the first 11 risk loci for myocardial infarction (MI) and coronary artery disease (CAD). Studies on quantitative traits provide an alternative approach to identify MI/CAD risk loci. This review captures the early successes in the emerging field of disease genomics.