You have full text access to this OnlineOpen article

Results of a worldwide survey on the assessment of platelet function by light transmission aggregometry: a report from the platelet physiology subcommittee of the SSC of the ISTH

  1. M. CATTANEO1,†,
  2. C. P .M. HAYWARD2,3,4,†,
  3. K. A. MOFFAT3,4,
  4. M. T. PUGLIANO1,
  5. Y. LIU3,
  6. A. D. MICHELSON5

Article first published online: 24 APR 2009

DOI: 10.1111/j.1538-7836.2009.03458.x

Issue

Journal of Thrombosis and Haemostasis

Journal of Thrombosis and Haemostasis

Volume 7, Issue 6, page 1029, June 2009

Additional Information

How to Cite

CATTANEO, M., HAYWARD, C. P. .M., MOFFAT, K. A., PUGLIANO, M. T., LIU, Y. and MICHELSON, A. D. (2009), Results of a worldwide survey on the assessment of platelet function by light transmission aggregometry: a report from the platelet physiology subcommittee of the SSC of the ISTH. Journal of Thrombosis and Haemostasis, 7: 1029. doi: 10.1111/j.1538-7836.2009.03458.x

Author Information

  1. 1

    Unità di Medicina III, Ospedale San Paolo, Dipartimento di Medicina, Chirurgia e Odontoiatria, Università di Milano, Milan, Italy

  2. 2

    Department of Pathology and Molecular Medicine

  3. 3

    Department of Medicine, McMaster University, Hamilton, Canada

  4. 4

    Hamilton Regional Laboratory Medicine Program, Hamilton, Canada

  5. 5

    Center for Platelet Research Studies, Division of Hematology/Oncology, Children’s Hospital Boston, Harvard Medical School, Boston, MA, USA

  1. †

    Equal authorship contributions.

*Marco Cattaneo, Unità di Medicina III, Ospedale San Paolo, Università di Milano, Via di Rudinì 8, 20142 Milan, Italy. Tel.: +39 0250323095; fax: +39 0250323090. E-mail: marco.cattaneo@unimi.it

  • †

    Equal authorship contributions.

Publication History

  1. Issue published online: 20 MAY 2009
  2. Article first published online: 24 APR 2009

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article (HTML) Get PDF (53K)

Cited in:

CrossRef

This article has been cited by:

  1. 1
    Kristi J. Smock, Robert L. Schmidt, Greg Hadlock, Greg Stoddard, David W. Grainger, Mark A. Munger, Assessment of orally dosed commercial silver nanoparticles on humanex vivoplatelet aggregation, Nanotoxicology, 2013, 1

    CrossRef

  2. 2
    Marcus D. Lancé, Yvonne M.C. Henskens, Patty Nelemans, Maurice H.S. Theunissen, Rene Van Oerle, Henri M. Spronk, Marco A.E. Marcus, Do blood collection methods influence whole-blood platelet function analysis?, Platelets, 2013, 24, 4, 275

    CrossRef

  3. 3
    M. Cattaneo, High on-treatment platelet reactivity – definition and measurement, Thrombosis and Haemostasis, 2013, 109, 5, 792

    CrossRef

  4. 4
    Bianca Rocca, Alfredo Dragani, Francesca Pagliaccia, Identifying determinants of variability to tailor aspirin therapy, Expert Review of Cardiovascular Therapy, 2013, 11, 3, 365

    CrossRef

  5. 5
    Michael Nagler, Silvio Kathriner, Lucas M. Bachmann, Walter A. Wuillemin, Impact of changes in haematocrit level and platelet count on thromboelastometry parameters, Thrombosis Research, 2013, 131, 3, 249

    CrossRef

  6. 6
    C. P. M. Hayward, Improving blood disorder diagnosis: reflections on the challenges, International Journal of Laboratory Hematology, 2013, 35, 3
    Direct Link:
  7. 7
    C. P. M. Hayward, K. A. Moffat, Laboratory testing for bleeding disorders: strategic uses of high and low-yield tests, International Journal of Laboratory Hematology, 2013, 35, 3
    Direct Link:
  8. 8
    Athanasios Karathanos, Tobias Geisler, Monitoring Aspirin and Clopidogrel Response: Testing Controversies and Recommendations, Molecular Diagnosis & Therapy, 2013,

    CrossRef

  9. 9
    Oliver M. Theusinger, Jerrold H. Levy, Point of Care Devices for Assessing Bleeding and Coagulation in the Trauma Patient, Anesthesiology Clinics, 2013, 31, 1, 55

    CrossRef

  10. 10
    A. Richardson, K. S. Sakariassen, J.-P. Meyer, P. Alberts, A. S. Sorensen, Single ascending oral dose pharmacokinetics and pharmacodynamics study of EV-077: the specific inhibitor of prostanoid- and isoprostane-induced cellular activation, European Journal of Clinical Pharmacology, 2013, 69, 3, 459

    CrossRef

  11. 11
    Elisabetta Ricottini, Fabio Mangiacapra, Germano Di Sciascio, Stent thrombosis and platelet reactivity, Cor et Vasa, 2013, 55, 2, e151

    CrossRef

  12. 12
    Marco Cattaneo, Platelets, 2013,

    CrossRef

  13. 13
    Paul Harrison, Marie Lordkipanidzé, Platelets, 2013,

    CrossRef

  14. 14
    Catherine P.M. Hayward, Karen A. Moffat, Platelets, 2013,

    CrossRef

  15. 15
    E. J. FAVALORO, J. KOUTTS, 2B or not 2B? Masquerading as von Willebrand disease?, Journal of Thrombosis and Haemostasis, 2012, 10, 2
    Direct Link:
  16. 16
    Catherine P.M. Hayward, Karen A. Moffat, Elizabeth Plumhoff, Elizabeth M. Van Cott, Approaches to investigating common bleeding disorders: An evaluation of North American coagulation laboratory practices, American Journal of Hematology, 2012, 87, S1
    Direct Link:
  17. 17
    Chunjian Li, Jack Hirsh, Debi Sloane, Yan Liang, Jianling Bai, Jeremy Paikin, Marilyn A. Johnston, Justin DeBeer, John W. Eikelboom, Aspirin response variability after major orthopedic surgery, Thrombosis Research, 2012, 130, 2, 216

    CrossRef

  18. 18
    M. MEROLLA, M. A. NARDI, J. S. BERGER, Centrifugation speed affects light transmission aggregometry, International Journal of Laboratory Hematology, 2012, 34, 1
    Direct Link:
  19. 19
    Eti Alessandra Femia, Mariateresa Pugliano, Gianmarco Podda, Marco Cattaneo, Comparison of different procedures to prepare platelet-rich plasma for studies of platelet aggregation by light transmission aggregometry, Platelets, 2012, 23, 1, 7

    CrossRef

  20. 20
    Gianmarco Podda, Eti Alessandra Femia, Mariateresa Pugliano, Marco Cattaneo, Congenital defects of platelet function, Platelets, 2012, 23, 7, 552

    CrossRef

  21. 21
    C Opländer, A Römer, A Paunel-Görgülü, T Fritsch, E E van Faassen, M Mürtz, A Bozkurt, G Grieb, Paul Fuchs, Norbert Pallua, C V Suschek, Dermal Application of Nitric Oxide In Vivo: Kinetics, Biological Responses, and Therapeutic Potential in Humans, Clinical Pharmacology & Therapeutics, 2012, 91, 6, 1074

    CrossRef

  22. 22
    Bo Wiinberg, Lisbeth R. Jessen, Inge Tarnow, Annemarie T. Kristensen, Diagnosis and treatment of platelet hyperactivity in relation to thrombosis in dogs and cats, Journal of Veterinary Emergency and Critical Care, 2012, 22, 1
    Direct Link:
  23. 23
    B. B. Dawood, G. C. Lowe, M. Lordkipanidze, D. Bem, M. E. Daly, M. Makris, A. Mumford, J. T. Wilde, S. P. Watson, Evaluation of participants with suspected heritable platelet function disorders including recommendation and validation of a streamlined agonist panel, Blood, 2012, 120, 25, 5041

    CrossRef

  24. You have free access to this content24
    Y. DARGAUD, B. SORENSEN, M. SHIMA, C. HAYWARD, A. SRIVASTAVA, C. NEGRIER, Global haemostasis and point of care testing, Haemophilia, 2012, 18,
    Direct Link:
  25. 25
    Patrizia Ferroni, Natale Vazzana, Silvia Riondino, Chiara Cuccurullo, Fiorella Guadagni, Giovanni Davì, Platelet Function in Health and Disease: from Molecular Mechanisms, Redox Considerations to Novel Therapeutic Opportunities, Antioxidants & Redox Signaling, 2012, 17, 10, 1447

    CrossRef

  26. 26
    M. CATTANEO, Response variability to clopidogrel: is tailored treatment, based on laboratory testing, the right solution?, Journal of Thrombosis and Haemostasis, 2012, 10, 3
    Direct Link:
  27. 27
    K. Okano, M. Araki, Y. Mimura, H. Nogaki, K. Ichihara, Simultaneous assay of activated platelet count and platelet-activating capacity by P-selectin detection using K2-EDTA-treated whole blood for antiplatelet agents, International Journal of Laboratory Hematology, 2012, 34, 6
    Direct Link:
  28. 28
    C. P. M. Hayward, K. A. Moffat, J.-F. Castilloux, Y. Liu, J. Seecharan, S. Tasneem, S. Carlino, A. Cormier, G. E. Rivard, Simultaneous measurement of adenosine triphosphate release and aggregation potentiates human platelet aggregation responses for some subjects, including persons with Quebec platelet disorder, Thrombosis and Haemostasis, 2012, 107, 4, 726

    CrossRef

  29. 29
    Natalia Rydz, Paula D. James, Why Is My Patient Bleeding Or Bruising?, Hematology/Oncology Clinics of North America, 2012, 26, 2, 321

    CrossRef

  30. 30
    J. F. Castilloux, K. A. Moffat, Y. Liu, J. Seecharan, M. Pai, C. P. M. Hayward, A prospective cohort study of light transmission platelet aggregometry for bleeding disorders: Is testing native platelet-rich plasma non-inferior to testing platelet count adjusted samples?, Thrombosis and Haemostasis, 2011, 106, 4, 675

    CrossRef

  31. 31
    Antonio Tello-Montoliu, Masafumi Ueno, Dominick J Angiolillo, Antiplatelet drug therapy: role of pharmacodynamic and genetic testing, Future Cardiology, 2011, 7, 3, 381

    CrossRef

  32. 32
    MICHAEL A. GAGLIA, REBECCA TORGUSON, RAJBABU PAKALA, ZHENYI XUE, GABRIEL SARDI, WILLIAM O. SUDDATH, KENNETH M. KENT, LOWELL F. SATLER, AUGUSTO D. PICHARD, RON WAKSMAN, Correlation between Light Transmission Aggregometry, VerifyNow P2Y12, and VASP-P Platelet Reactivity Assays Following Percutaneous Coronary Intervention, Journal of Interventional Cardiology, 2011, 24, 6
    Direct Link:
  33. 33
    Catherine P.M. Hayward, Diagnostic evaluation of platelet function disorders, Blood Reviews, 2011, 25, 4, 169

    CrossRef

  34. 34
    E. J. FAVALORO, R. BONAR, External quality assurance for the PFA-100®, Journal of Thrombosis and Haemostasis, 2011, 9, 4
    Direct Link:
  35. You have free access to this content35
    Paul Harrison, Ian Mackie, Andrew Mumford, Carol Briggs, Ri Liesner, Mark Winter, Sam Machin, Guidelines for the laboratory investigation of heritable disorders of platelet function, British Journal of Haematology, 2011, 155, 1
    Direct Link:
  36. 36
    D. Sibbing, R. A. Byrne, I. Bernlochner, A. Kastrati, High platelet reactivity and clinical outcome – Fact and fiction, Thrombosis and Haemostasis, 2011, 106, 2, 191

    CrossRef

  37. 37
    P. C. J. ARMSTRONG, P. D. LEADBEATER, M. V. CHAN, N. S. KIRKBY, J. A. JAKUBOWSKI, J. A. MITCHELL, T. D. WARNER, In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation, Journal of Thrombosis and Haemostasis, 2011, 9, 3
    Direct Link:
  38. 38
    Rita Paniccia, Emilia Antonucci, Niccolò Maggini, Marco Miranda, Eloisa Romano, Anna Maria Gori, Rossella Marcucci, Domenico Prisco, Rosanna Abbate, Light Transmittance Aggregometry Induced by Different Concentrations of Adenosine Diphosphate to Monitor Clopidogrel Therapy: A Methodological Study, Therapeutic Drug Monitoring, 2011, 33, 1, 94

    CrossRef

  39. 39
    Nalyaka Sambu, Nick Curzen, Monitoring the effectiveness of antiplatelet therapy: opportunities and limitations, British Journal of Clinical Pharmacology, 2011, 72, 4
    Direct Link:
  40. 40
    Melissa V. Chan, Paul C. J. Armstrong, Francesco Papalia, Nicholas S. Kirkby, Timothy D. Warner, Optical multichannel (optimul) platelet aggregometry in 96-well plates as an additional method of platelet reactivity testing, Platelets, 2011, 22, 7, 485

    CrossRef

  41. 41
    Sara J. Israels, Walter H.A. Kahr, Victor S. Blanchette, Naomi L.C. Luban, Georges E. Rivard, Margaret L. Rand, Platelet disorders in children: A diagnostic approach, Pediatric Blood & Cancer, 2011, 56, 6
    Direct Link:
  42. 42
    Helen Mani, Mirna Hellis, Edelgard Lindhoff-Last, Platelet function testing in hirudin and BAPA anticoagulated blood, Clinical Chemistry and Laboratory Medicine, 2011, 49, 3

    CrossRef

  43. 43
    J. ULEHLOVA, L. SLAVIK, V. KRCOVA, M. HUTYRA, J. GALUSZKA, K. INDRAK, The assessment of aspirin resistance by using light transmission and multiple electrode aggregometry, International Journal of Laboratory Hematology, 2011, 33, 3
    Direct Link:
  44. 44
    M. Cattaneo, The Clinical Relevance of Response Variability to Antiplatelet Therapy, Hematology, 2011, 2011, 1, 70

    CrossRef

  45. 45
    Jun Yamanouchi, Takaaki Hato, Toshiyuki Niiya, Kou Nakagawa, Yoshiaki Kumon, Hiroshi Fujiwara, Yoshihiro Yakushijin, Masaki Yasukawa, Vasodilator-stimulated phosphoprotein (VASP) phosphorylation assay for platelet response to cilostazol, Platelets, 2011, 22, 2, 135

    CrossRef

  46. 46
    A. D. Mumford, B. B. Dawood, M. E. Daly, S. L. Murden, M. D. Williams, M. B. Protty, J. C. Spalton, M. Wheatley, S. J. Mundell, S. P. Watson, A novel thromboxane A2 receptor D304N variant that abrogates ligand binding in a patient with a bleeding diathesis, Blood, 2010, 115, 2, 363

    CrossRef

  47. You have free access to this content47
    Alfredo Dragani, Francesco Brancati, Silvia Pascale, Domenico Mattoscio, Bianca Rocca, Clinical and laboratory phenotype associated with the aspirin-like defect, British Journal of Haematology, 2010, 148, 4
    Direct Link:
  48. 48
    Laurent Bonello, Udaya S. Tantry, Rossella Marcucci, Ruediger Blindt, Dominick J. Angiolillo, Richard Becker, Deepak L. Bhatt, Marco Cattaneo, Jean Philippe Collet, Thomas Cuisset, Christian Gachet, Gilles Montalescot, Lisa K. Jennings, Dean Kereiakes, Dirk Sibbing, Dietmar Trenk, Jochem W. Van Werkum, Franck Paganelli, Matthew J. Price, Ron Waksman, Paul A. Gurbel, Consensus and Future Directions on the Definition of High On-Treatment Platelet Reactivity to Adenosine Diphosphate, Journal of the American College of Cardiology, 2010, 56, 12, 919

    CrossRef

  49. 49
    Emmanuel J. Favaloro, Giuseppe Lippi, Massimo Franchini, Contemporary platelet function testing, Clinical Chemistry and Laboratory Medicine, 2010, 48, 5

    CrossRef

  50. You have free access to this content50
    S. KITCHEN, C. HAYWARD, C. NEGRIER, Y. DARGAUD, New developments in laboratory diagnosis and monitoring, Haemophilia, 2010, 16,
    Direct Link:
  51. 51
    Lourdes Basabe-Desmonts, Gerardene Meade, Dermot Kenny, New trends in bioanalytical microdevices to assess platelet function, Expert Review of Molecular Diagnostics, 2010, 10, 7, 869

    CrossRef

  52. 52
    A. R. Rechner, Platelet function testing in clinical diagnostics, Hämostaseologie, 2010, 31, 2, 79

    CrossRef

  53. 53
    W. Streif, Olivieri Martin, Weickardt Stefan, Eberl Wolfgang, Knoefler Ralf, On Behalf of the Thromkid Study Gro, Testing for inherited platelet defects in clinical laboratories in Germany, Austria and Switzerland. Results of a survey carried out by the Permanent Paediatric Group of the German Thrombosis and Haemostasis Research Society (GTH), Platelets, 2010, 21, 6, 470

    CrossRef

  54. 54
    Martin W. Besser, Andrew A. Klein, The coagulopathy of cardiopulmonary bypass, Critical Reviews in Clinical Laboratory Sciences, 2010, 47, 5-6, 197

    CrossRef

  55. 55
    Mojca Stegnar, Anja Kneževič, Mojca Božič-Mijovski, The effect of pre-analytical variables on light transmittance aggregometry in citrated platelet-rich plasma from healthy subjects, Clinical Chemistry and Laboratory Medicine, 2010, 48, 10

    CrossRef

  56. 56
    L. Brass, Understanding and Evaluating Platelet Function, Hematology, 2010, 2010, 1, 387

    CrossRef

  57. 57
    K. Boeer, M. Reinhöfer, W. Lösche, Validation of a procedure to assess ASA-response in patients with decreased, initial TRAP induced aggregation, Platelets, 2010, 21, 5, 314

    CrossRef

  58. 58
    Teresa Quiroga, Manuela Goycoolea, Valeria Matus, Pamela Zúñiga, Carlos Martínez, Marcelo Garrido, Eduardo Aranda, Federico Leighton, Olga Panes, Jaime Pereira, Diego Mezzano, Diagnosis of mild platelet function disorders. Reliability and usefulness of light transmission platelet aggregation and serotonin secretion assays, British Journal of Haematology, 2009, 147, 5
    Direct Link:
  59. 59
    Abdul-Majeed Albanyan, Kampta Sukhu, Paul Harrison, Evaluation of the PDQ™ centrifuge for preparing platelet rich, platelet poor and platelet free plasma samples for light transmission aggregometry and microparticle measurement, Platelets, 2009, 20, 8, 610

    CrossRef

  60. 60
    N. J. TRUSS, P. C. J. ARMSTRONG, E. LIVERANI, I. VOJNOVIC, T. D. WARNER, Heparin but not citrate anticoagulation of blood preserves platelet function for prolonged periods, Journal of Thrombosis and Haemostasis, 2009, 7, 11
    Direct Link:
  61. 61
    Paul Harrison, David Keeling, Platelet Assays and Platelet Dysfunction,
    Direct Link:
View Full Article (HTML) Get PDF (53K)