Heparin promotes soluble VEGF receptor expression in human placental villi to impair endothelial VEGF signaling
Article first published online: 1 DEC 2011
© 2011 International Society on Thrombosis and Haemostasis
Journal of Thrombosis and Haemostasis
Volume 9, Issue 12, pages 2486–2497, December 2011
How to Cite
DREWLO, S., LEVYTSKA, K., SOBEL, M., BACZYK, D., LYE, S. J. and KINGDOM, J. C. P. (2011), Heparin promotes soluble VEGF receptor expression in human placental villi to impair endothelial VEGF signaling. Journal of Thrombosis and Haemostasis, 9: 2486–2497. doi: 10.1111/j.1538-7836.2011.04526.x
- Issue published online: 1 DEC 2011
- Article first published online: 1 DEC 2011
- Accepted manuscript online: 7 OCT 2011 08:14AM EST
- Received 5 July 2011, accepted 26 September 2011
Data S1. Material and Methods.
Figure S1. sFLT1 secretion of term, 8–15 weeks, IUGR, PE mixed with IUGR and PE placental villi (pg mL−1*mg tissue).
Figure S2. Total FLT1 was stained in different tissues incubated with or without LMWH (0.25 IU mL−1).
Figure S3.‘De-novo’ synthesized and preformed release of sFLT1 from first trimester explants in response to heparin treatment.
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