• 1
    Rathbun SW, Raskob G, Whitsett TL. Sensitivity and specificity of helical computed tomography in the diagnosis of pulmonary embolism: a systematic review. Ann Intern Med 2000; 132: 22732.
  • 2
    Mullins MD, Becker DM, Hagspiel KD, Philbrick JT. The role of spiral volumetric computed tomography in the diagnosis of pulmonary embolism. Arch Intern Med 2000; 160: 2938.
  • 3
    Le Gal G, Righini M, Parent F, van Strijen M, Couturaud F. Diagnosis and management of subsegmental pulmonary embolism. J Thromb Haemost 2006; 4: 72431.
  • 4
    Ghaye B, Szapiro D, Mastora I, Delannoy V, Duhamel A, Remy J, Remy-Jardin M. Peripheral pulmonary arteries: how far in the lung does multi-detector row spiral CT allow analysis? Radiology 2001; 219: 62936.
  • 5
    Carrier M, Righini M, Wells PS, Perrier A, Anderson DR, Rodger MA, Pleasance S, Le Gal G. Subsegmental pulmonary embolism diagnosed by computed tomography: incidence and clinical implications. A systematic review and meta-analysis of the management outcome studies. J Thromb Haemost 2010; 8: 171622.
  • 6
    Wiener RS, Schwartz LM, Woloshin S. Time trends in pulmonary embolism in the United States: evidence of overdiagnosis. Arch Intern Med 2011; 171: 8317.
  • 7
    DeMonaco NA, Dang Q, Kapoor WN, Ragni MV. Pulmonary embolism incidence is increasing with use of spiral computed tomography. Am J Med 2008; 121: 6117.
  • 8
    Carrier M, Kimpton M, Le Gal G, Kahn SR, Kovacs MJ, Wells PS, Anderson DR, Rodger MA. The management of a sub-segmental pulmonary embolism: a cross-sectional survey of Canadian thrombosis physicians. J Thromb Haemost 2011; 9: 14125.
  • 9
    Schulman S, Kearon C. Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients. J Thromb Haemost 2005; 3: 6924.
  • 10
    Costantino G, Norsa AH, Amadori R, Ippolito S, Resta F, Bianco R, Casazza G, Biagiotti S, Rusconi AM, Montano N. Interobserver agreement in the interpretation of computed tomography in acute pulmonary embolism. Am J Emerg Med 2009; 27: 110911.
  • 11
    Ghanima W, Nielssen BE, Holmen LO, Witwit A, Al-Ashtari A, Sandset PM. Multidetector computed tomography (MDCT) in the diagnosis of pulmonary embolism: interobserver agreement among radiologists with varied levels of experience. Acta Radiol 2007; 48: 16570.
  • 12
    Eyer BA, Goodman LR, Washington L. Clinicians’ response to radiologists’ reports of isolated subsegmental pulmonary embolism or inconclusive interpretation of pulmonary embolism using MDCT. AJR Am J Roentgenol 2005; 184: 6238.
  • 13
    Goodman LR. Small pulmonary emboli: what do we know? Radiology 2005; 234: 6548.
  • 14
    Auer RC, Schulman AR, Tuorto S, Gonen M, Gonsalves J, Schwartz L, Ginsberg MS, Fong Y. Use of helical CT is associated with an increased incidence of postoperative pulmonary emboli in cancer patients with no change in the number of fatal pulmonary emboli. J Am Coll Surg 2009; 208: 8718.
  • 15
    Anderson DR, Kahn SR, Rodger MA, Kovacs MJ, Morris T, Hirsch A, Lang E, Stiell I, Kovacs G, Dreyer J, Dennie C, Cartier Y, Barnes D, Burton E, Pleasance S, Skedgel C, O’Rouke K, Wells PS. Computed tomographic pulmonary angiography vs ventilation-perfusion lung scanning in patients with suspected pulmonary embolism: a randomized controlled trial. JAMA 2007; 298: 274353.
  • 16
    Donato AA, Khoche S, Santora J, Wagner B. Clinical outcomes in patients with isolated subsegmental pulmonary emboli diagnosed by multidetector CT pulmonary angiography. Thromb Res 2010; 126: e26670.
  • 17
    Kearon C, Kahn SR, Agnelli G, Goldhaber SZ, Raskob GE, Comerota AJ. Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians Evidence-based Clinical Practice Guidelines (8th edition). Chest 2008; 133: 454545.