Fibrinogen γ-chain peptide-coated, ADP-encapsulated liposomes rescue thrombocytopenic rabbits from non-compressible liver hemorrhage
Article first published online: 1 OCT 2012
© 2012 International Society on Thrombosis and Haemostasis
Journal of Thrombosis and Haemostasis
Volume 10, Issue 10, pages 2137–2148, October 2012
How to Cite
NISHIKAWA, K., HAGISAWA, K., KINOSHITA, M., SHONO, S., KATSUNO, S., DOI, M., YANAGAWA, R., SUZUKI, H., IWAYA, K., SAITOH, D., SAKAMOTO, T., SEKI, S., TAKEOKA, S. and HANDA, M. (2012), Fibrinogen γ-chain peptide-coated, ADP-encapsulated liposomes rescue thrombocytopenic rabbits from non-compressible liver hemorrhage. Journal of Thrombosis and Haemostasis, 10: 2137–2148. doi: 10.1111/j.1538-7836.2012.04889.x
- Issue published online: 1 OCT 2012
- Article first published online: 1 OCT 2012
- Accepted manuscript online: 20 AUG 2012 10:20AM EST
- Received 9 March 2012, accepted 30 July 2012
Fig. S1. Scheme of blood withdrawal from rabbits; preparations of PRP, PPP, and washed RBC, and transfusion of washed RBC into rabbits.
Fig. S2. Non-compressible liver hemorrhage in thrombocytopenic rabbits.
Fig. S3. Changes in hematological parameters by blood exchange.
Fig. S4. Histological findings of the lung, liver, kidney and spleen 2 weeks after administration of H12-(ADP)-liposomes and liver hemorrhage in the thrombocytopenic rabbits.
Table S1. Changes in coagulation factors in rabbits after blood exchange.
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