Financial disclosures: none.
A Case of Cardiomyopathy Induced by Inappropriate Sinus Tachycardia and Cured by Ivabradine
Article first published online: 23 JUN 2009
©2009, The Authors. Journal compilation ©2009 Wiley Periodicals, Inc.
Pacing and Clinical Electrophysiology
Volume 32, Issue 7, pages 942–944, July 2009
How to Cite
WINUM, P.-F., CAYLA, G., RUBINI, M., BECK, L. and MESSNER-PELLENC, P. (2009), A Case of Cardiomyopathy Induced by Inappropriate Sinus Tachycardia and Cured by Ivabradine. Pacing and Clinical Electrophysiology, 32: 942–944. doi: 10.1111/j.1540-8159.2009.02414.x
- Issue published online: 23 JUN 2009
- Article first published online: 23 JUN 2009
- Received January 15, 2009; revised February 8, 2009; accepted March 22, 2009.
- inappropriate sinus tachycardia;
- heart failure;
- tachycardia-induced cardiomyopathy
We present the case of a 67-year-old woman with cardiomyopathy induced by inappropriate sinus tachycardia (IST) and a particularly high average heart rate. The patient was resistant and/or intolerant to treatment with conventional rate-slowing medications. We used ivabradine—a specific sinus node If current inhibitor—and successfully lowered the heart rate (33 beats per minute mean heart rate decrease). Symptoms, systolic function, and heart rate variability parameters recovered dramatically. No side effect was noted. We suggest that ivabradine—evaluated in trials to treat stable angina—should be considered as a second-line treatment in patients with very symptomatic and refractory IST.