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Hypothyroid Patient with Brugada Electrocardiographic Waveforms: Case Report


Address for reprints: Yong-hui Zhao, Department of Cardiology, Henan Provincial People's Hospital, 7 Wei-wu Avenue, Zhengzhou 453003, China. Fax +86 371 65580238; email:


We report a 46-year-old man who presented with hypothyroidism. An electrocardiogram obtained at the time of the first examination revealed Brugada electrocardiographic (Brugada-ECG) waveforms in leads V1 to V3. The patient and his family had no history of arrhythmia and syncopal attack. The Brugada-ECG waveforms disappeared with the normalization of thyroid function. The case suggested that hypothyroidism could lead to secondary Brugada-ECG waveforms because of its effect on myocardial ion channels. (PACE 2012; 35:e222–e225)