Atrial Selective Effect of Amiodarone to Increase Threshold of Excitation
Article first published online: 2 DEC 2011
©2011, The Authors. Journal compilation ©2011 Wiley Periodicals, Inc.
Pacing and Clinical Electrophysiology
Volume 36, Issue 3, pages e93–e96, March 2013
How to Cite
GRANDE, J. M., GRANDE, A., MOLINA, M., NOVO, C. and CABESTRERO, F. (2013), Atrial Selective Effect of Amiodarone to Increase Threshold of Excitation. Pacing and Clinical Electrophysiology, 36: e93–e96. doi: 10.1111/j.1540-8159.2011.03272.x
- Issue published online: 5 MAR 2013
- Article first published online: 2 DEC 2011
- Manuscript Accepted: 14 JUN 2011
- Manuscript Revised: 9 JUN 2011
- Manuscript Received: 4 JAN 2011
- atrial excitation
Increases of pacing threshold stimulation are well documented with different antiarrhythmic drugs, but not with amiodarone. We report a case of a patient with dual-chamber pacing, with stable thresholds on repeated measurements on the last year, who presented severe increase of atrial pacing threshold resulting in loss of atrial capture after a year of treatment with amiodarone. Thresholds were normalized once amiodarone was removed. Ventricular thresholds were not affected.