Giovanni Raciti is employed by Guidant, Inc.
Atrial Fibrillation in Patients with a Dual Defibrillator: Characteristics of Spontaneous and Induced Episodes and Effect of Ventricular Tachyarrhythmia Induction
Article first published online: 11 MAY 2005
Journal of Cardiovascular Electrophysiology
Volume 16, Issue 9, pages 974–980, September 2005
How to Cite
BORIANI, G., RAVIELE, A., BIFFI, M., GASPARINI, G., MARTIGNANI, C., VALZANIA, C., DIEMBERGER, I., CORRADO, A., RACITI, G. and BRANZI, A. (2005), Atrial Fibrillation in Patients with a Dual Defibrillator: Characteristics of Spontaneous and Induced Episodes and Effect of Ventricular Tachyarrhythmia Induction. Journal of Cardiovascular Electrophysiology, 16: 974–980. doi: 10.1111/j.1540-8167.2005.50009.x
Manuscript received 5 January 2005; Revised manuscript received 8 March 2005; Accepted for publication 10 March 2005.
- Issue published online: 31 AUG 2005
- Article first published online: 11 MAY 2005
- atrial fibrillation;
- implantable defibrillator;
- ventricular fibrillation;
- ventricular tachycardia;
- sudden death
Background: The pattern of FF intervals during atrial fibrillation (AF) has been analyzed in induced and spontaneous AF episodes, after the induction of ventricular fibrillation (VF) and after atrial shock, in order to suggest practical considerations for AF management in patients implanted with antitachycardia devices.
Methods: In 13 patients implanted with a dual-chamber defibrillator, FF intervals were analyzed during two separate induced AF episodes, before and after VF induction over AF, as well as during spontaneous AF episodes and after unsuccessful atrial shocks. The following parameters were considered: mean atrial cycle length (CL), atrial CL stability, and standard deviation of the atrial cycle.
Results: The AF pattern had comparable characteristics considering two separate inductions of AF, as well as spontaneous AF episodes. Ventricular tachyarrhythmia induction resulted in a shortening of atrial CL (P < 0.02) and in a less organized AF pattern (P < 0.005). Changes in the FF interval after ineffective shock therapy showed a shortening of AF cycles after shocks with energies far below the defibrillation threshold.
Conclusions: (a) The AF pattern is reproducible in separate inductions of sustained AF and in spontaneous episodes, (b) dynamic changes involving a shortening of the AF cycle and an evolution to a less homogeneous pattern occur after VF induction, revealing a complex interplay between AF and VF, and (c) FF interval analysis after ineffective shock delivery may allow the relationship between delivered shock energy and effective defibrillation energy to be estimated, thereby providing practical suggestions for step-up protocols in atrial cardioversion.