Atrioventricular Nodal Reentrant Tachycardia in Two Siblings with Wolfram Syndrome


  • Manuscript received 16 February 2006; Revised manuscript received 4 April 2006; Accepted for publication 7 April 2006.

Address for correspondence: Peter J. Zimetbaum, M.D., Beth Israel Deaconess Medical Center Division of Cardiology – Baker 4 Boston, MA 02215 telephone: 617-632-7458. fax: 617-632-7377; Email:


This is a case of two siblings with the autosomal recessive Wolfram syndrome who both have documented atrioventricular nodal reentrant tachycardia (AVNRT). This is the first report to our knowledge that links AVNRT to a syndrome in which the putative gene has been identified.