Endomyocardial Biopsy Guided by Electroanatomic Voltage Mapping in Arrhythmogenic Right Ventricular Cardiomyopathy: A Case Report


  • Manuscript received 6 November 2006; Revised manuscript received 24 January 2007; Accepted for publication 29 January 2007.

Address for correspondence: Andrea Avella, M.D., Cardiology Division, Cardiac Arrhythmia Center and Heart Failure Unit, St. Camillo-Forlanini Hospital, Via Portuense 332, 00149, Rome, Italy. Fax: +39-06-58704545; E-mail: andrea.avella@alice.it and andrea.avella@tin.it


A positive endomyocardial biopsy (EMB) is a major diagnostic criterion for arrhythmogenic right ventricular cardiomyopathy (ARVC). Nevertheless, its sensitivity is low due to the focal nature of the disease. Moreover, myocardial samples are usually taken from the uncommonly involved interventricular septum to minimize the risk of perforation. In this report, we describe a novel bioptical approach for ARVC diagnosis guided by the identification of right ventricle (RV) affected regions by means of electroanatomical voltage mapping.