This work was supported by a 21C Frontier R&D Grant #SC3140.
Hybrid Epicardial and Endocardial Ablation of Persistent or Permanent Atrial Fibrillation: A New Approach for Difficult Cases
Version of Record online: 16 JUN 2007
Journal of Cardiovascular Electrophysiology
Volume 18, Issue 9, pages 917–923, September 2007
How to Cite
PAK, H.-N., HWANG, C., LIM, H. E., KIM, J. S. and KIM, Y.-H. (2007), Hybrid Epicardial and Endocardial Ablation of Persistent or Permanent Atrial Fibrillation: A New Approach for Difficult Cases. Journal of Cardiovascular Electrophysiology, 18: 917–923. doi: 10.1111/j.1540-8167.2007.00882.x
Manuscript received 25 February 2007; Revised manuscript received 14 April 2007; Accepted for publication 2 May 2007.
- Issue online: 16 JUN 2007
- Version of Record online: 16 JUN 2007
- epicardial ablation;
- atrial fibrillation;
- catheter ablation
Background: Although percutaneous epicardial catheter ablation (PECA) has been used for the management of epicardial ventricular tachycardia, the use of PECA for atrial fibrillation (AF) has not yet been reported.
Objective: To evaluate the efficacy and feasibility of a hybrid PECA and endocardial ablation for AF.
Methods: We performed PECA for AF in five patients (48.6 ± 8.1 years old, all male, four redo ablation procedures of persistent AF with a risk of pulmonary vein (PV) stenosis, one de novo ablation of permanent [AF]) after an endocardial AF ablation guided by PV potentials and 3D mapping (NavX). Utilizing an open irrigation tip catheter, a left atrial (LA) linear ablation from the roof to the perimitral isthmus or localized ablation at the junction between the LA appendage and left-sided PVs or ligament of Marshall (LOM) was performed.
Results: PECA of AF was successful in all patients with an ablation time of <15 minutes. The left-sided PV potentials were eliminated by PECA in all patients. Bidirectional block of the perimitral line was achieved in two of two patients and a left inferior PV tachycardia with conduction block to the LA was observed during the ablation in the area of the LOM in one patient. A hemopericardium developed in one patient, but was controlled successfully. During 8.0 ± 6.3 months of follow-up, all patients have remained in sinus rhythm (four patients without antiarrhythmic drugs).
Conclusion: A hybrid PECA of AF is feasible and effective in patients with redo-AF ablation procedures and at risk for left-sided PV stenosis or who are resistant to endocardial linear ablation.