Manuscript received 16 November 2007; Revised manuscript received 6 February 2008; Accepted for publication 8 February 2008.
When an ICD is Not the Answer… Hypothyroidism-Induced Cardiomyopathy and Torsades de Pointes
Article first published online: 8 APR 2008
© 2008 Wiley Periodicals, Inc.
Journal of Cardiovascular Electrophysiology
Volume 19, Issue 10, pages 1105–1107, October 2008
How to Cite
ELLIS, C. R. and MURRAY, K. T. (2008), When an ICD is Not the Answer… Hypothyroidism-Induced Cardiomyopathy and Torsades de Pointes. Journal of Cardiovascular Electrophysiology, 19: 1105–1107. doi: 10.1111/j.1540-8167.2008.01154.x
- Issue published online: 20 SEP 2008
- Article first published online: 8 APR 2008
- torsades de pointes;
- ventricular tachycardia
Introduction: An increasing number of patients with left ventricular (LV) dysfunction are referred for placement of an implantable cardioverter-defibrillator (ICD).
Case Report: A 78-year-old female with fatigue, palpitations, and presyncope was referred for consideration of an ICD because of a cardiomyopathy and nonsustained ventricular tachycardia (VT). Her evaluation revealed severe hypothyroidism, marked QT prolongation, and episodes of torsades de pointes. With levothyroxine therapy, her ventricular arrhythmias rapidly abated, with subsequent normalization of LV function and the QT interval.
Conclusions: This report highlights the critical importance of detecting hypothyroidism as an unusual cause for reversible cardiomyopathy and ventricular arrhythmias.