Dr. K. Suenari and Dr. Y.-F. Hu contributed equally to this study.
Gender Differences in the Clinical Characteristics and Atrioventricular Nodal Conduction Properties in Patients With Atrioventricular Nodal Reentrant Tachycardia
Article first published online: 28 APR 2010
© 2010 Wiley Periodicals, Inc.
Journal of Cardiovascular Electrophysiology
Volume 21, Issue 10, pages 1114–1119, October 2010
How to Cite
SUENARI, K., HU, Y.-F., TSAO, H.-M., TAI, C.-T., CHIANG, C.-E., LIN, Y.-J., CHANG, S.-L., LO, L.-W., TA-CHUAN, T., LEE, P.-C., TUNG, N. H., HUANG, S.-Y., WU, T.-J. and CHEN, S.-A. (2010), Gender Differences in the Clinical Characteristics and Atrioventricular Nodal Conduction Properties in Patients With Atrioventricular Nodal Reentrant Tachycardia. Journal of Cardiovascular Electrophysiology, 21: 1114–1119. doi: 10.1111/j.1540-8167.2010.01779.x
Dr. T.-J. Wu is a principal investigator on research grants TCVGH-983107C (Taichung, Taiwan), NSC 98-2314-B-010-033-MY2 (Taipei, Taiwan), and NSC 98-2314-B-075A-011-MY2 (Taipei, Taiwan).
- Issue published online: 28 APR 2010
- Article first published online: 28 APR 2010
- Manuscript received 3 January 2010; Revised manuscript received 8 March 2010; Accepted for publication 12 March 2010.
- atrioventricular nodal reentrant tachycardia;
- autonomic nervous system;
- catheter ablation;
Gender Differences in Patients With AVNRT. Introduction: The detailed electrophysiological characteristics of the gender differences associated with atrioventricular nodal reentrant tachycardia (AVNRT) have not been clarified. This study investigated the gender-related electrophysiological differences in a large series of patients undergoing radiofrequency catheter ablation.
Methods and Results: A total of 2,088 consecutive AVNRT patients (men/women 869/1,219) who underwent catheter ablation were enrolled in this study. We evaluated the gender differences in their electrophysiological characteristics. Women had a significantly younger age of onset, higher incidence of multiple jumps, shorter AH interval, atrial effective refractory period (ERP), anterograde fast pathway ERP, anterograde slow pathway ERP, and retrograde slow pathway ERP, and longer ventricular ERP than men. The incidence of baseline ventriculoatrial dissociation was lower in women than in men. Women needed less isoproterenol/atropine to induce AVNRT. No gender differences in the radiation exposure time, procedure time, complication rate, acute success rate, or second procedure rate were noted. Both typical and atypical AVNRT were more predominant in women. In the patients with atypical AVNRT, there was no significant gender difference in incidence of baseline ventriculoatrial dissociation; however, the retrograde slow pathway ERP was significantly shorter in women than in men. Women of premenopausal age (≤50 years old) had a significantly higher incidence of anterograde multiple jumps and a retrograde jump phenomenon, and a shorter anterograde slow pathway ERP and retrograde slow pathway ERP than those of women over 50 years old.
Conclusion: Gender differences in the anterograde and retrograde AV nodal electrophysiology were noted in the patients with AVNRT. (J Cardiovasc Electrophysiol, Vol. 21, pp. 1114-1119)